期刊文献+

多囊卵巢综合征与脂肪因子相关性的研究进展 被引量:6

Research progress of correlation between polycystic ovary syndrome and adipokines
下载PDF
导出
摘要 多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期妇女最常见的一种内分泌及代谢紊乱性疾病,其主要特征为肥胖、胰岛素抵抗、高雄激素表现、持续性无排卵以及卵巢多囊样改变等。近年来发现肥胖与PCOS的发生有着密切的联系,随着对脂肪细胞的内分泌作用进一步了解,逐渐认识到脂肪所产生的脂肪细胞因子可能是导致PCOS发生的重要因素之一。现就国内外这一方面的研究进展做一综述。 Polycystic ovary syndrome(PCOS)is one of the most common diseases of endocrine and metabolic disorder in women of reproductive age.It's characterized by obesity,insulin resistance,hyperandrogenism,chronic anovulation and polycystic ovaries.In recent year,it is found that the occurrence of PCOS is closely related to adipokines.With the further understanding the endocrine of adipose tissue,it is found that adipokines may be one of the important factors leading to the occurrence of PCOS.This paper reviews the research progress in correlations between polycystic ovary syndrome and adipokines.
作者 付鑫 王蔼明
出处 《生殖医学杂志》 CAS 2014年第9期776-779,共4页 Journal of Reproductive Medicine
基金 军队"十一五"科技攻关课题(06G006)
关键词 多囊卵巢综合征 肥胖 脂肪细胞因子 Polycystic ovary syndrome Obesity Adipokines
  • 相关文献

参考文献2

二级参考文献21

  • 1卢希平,王波,黄荷凤.非肥胖多囊卵巢综合征不孕患者瘦素mRNA和蛋白表达的对照研究[J].中华医学杂志,2005,85(2):88-91. 被引量:4
  • 2Rebecca S B,Susan E M,Paul T et al.Suppression of leptin during lactation: contribution of the suckling stimulus versus milk production[].The Journal of Endocrinology.1999
  • 3Friedman J M.Leptin,leptin receptors and the control of body weight[].European Journal of Medical Research.1997
  • 4B?tzow T L,Moilanen J M,Lehtovitrta M et al.Serum and follicular fluid leptin during in vitro fertilization: rela- tionship among leptin increase,body fat mass,and re- duced ovarian response[].The Journal of Clinical Endocrinology.1999
  • 5Robert J N,Manny N,Ruijin W et al.Improving repro- ductive performance in overweight/obese women with ef- fective weight management[].Human Reproduction Update.2004
  • 6Cioffi JA,Van Blerkom J,Antczak M et al.The expres- sion of leptin and its receptor in preovulatory human folli- cles[].Molecular Human Reproduction.1997
  • 7Hisham A S,Mohamed A,Magdy M et al.Serum leptin elevation in obese women with PCOS: a continuing con- troversy[].Journal of Assisted Reproduction and Genetics.2004
  • 8Van Blerkom J,Antczak M,Schrader R.The developmen- tal potential of the human oocyte is related to the dis- solved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics[].Human Reproduction.1997
  • 9Loffler S,Aust G,Kohler U et al.Evidence of leptin ex- pression in normal and polycystic human ovaries[].Molecular Human Reproduction.2001
  • 10Agarwal S K,Vogel K,Weitsman SR et al.Leptin antago- nizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary[].The Journal of Clinical Endocrinology.1999

共引文献18

同被引文献70

  • 1杨涛,杨永年.Exenatide和β细胞功能[J].国外医学(内分泌学分册),2005,25(1):18-22. 被引量:9
  • 2蔡志明,李蓉,卢丽华,郝桂琴.胰岛素抵抗与多囊卵巢综合征[J].生殖医学杂志,2005,14(3):189-192. 被引量:18
  • 3Jensterle M, Sebestjen M,Janez A,et al.Improvement of en-dothelial function with metformin and rosiglitazone treatmentin women with polycystic ovary syndrome [J]. Eur J En-docrinol ,2008,159(4):399-406.
  • 4Ebrahimi-Mamaghani M, Saghafi-Asl M, Pirouzpanah S,et al. Association of insulin resistance with lipid profile,metabolic syndrome, and hormonal aberrations in over-weight or obese women with polycystic ovary syndrome[J]. JHealth Popul Nutr,2015,33( 1): 157-167.
  • 5Jensterle M,Kravos NA,Pfeifer M,et al. A 12 -weektreatment with the long-acting glucagon-like peptide 1 re-ceptor agonist liraglutide leads to significant weight loss in asubset of obese women with newly diagnosed polycystic o-vary syndrome[J]. Hormones (Athens),2015,14( 1) :81-90.
  • 6Jezovnik MK, Jensterle SM, Janez A, et al. Comparison ofdifferent methods investigating functional and morphologicalmarkers of early atherogenesis in obese women with poly-cystic ovary syndrome[J]. Int Angiol,2015,14( 1) :81-90.
  • 7Kahal H, Aburima A, Ungvari T, et al. The effects oftreatment with liraglutide on atherothrombotic risk in obeseyoung women with polycystic ovary syndrome and controls[J].BMC Endocrine Disorders,2015,15( 1): 112-117.
  • 8Norman RJ, Dewailly D, Legro RS, et al. Polycystic ovary synclrome[J]. Lancet,2007,370 : 685 697.
  • 9Azziz R, Woods KS, Reyna R, et al. The prevalence and features of the polycyste ovary syndrome in an unseiected population [ J ]J Clin Endoerinol Metab, 2004, 89: 2745 2749.
  • 10Ehrmann DA. Polycystic ovary syndrome[J]. N Engl J Med, 2005,352:1223-1236.

引证文献6

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部