摘要
目的:探讨负压封闭引流联合抗生素植骨治疗慢性骨髓炎的临床效果。方法:回顾性分析我院收治的慢性骨髓炎患者,对照组采用传统的慢性骨髓炎的治疗方法进行治疗,实验组采用负压封闭引流术联合抗生素植骨治疗,比较两组患者的疗效、复发率和住院时间。结果:对照组总有效率为72.7%;实验组总有效率为100%。对照组复发率为22.7%,细菌检出率为27.2%;对照组复发率为4.3%,细菌检出率为4.3%。对照组伤口平均愈合时间为(48.3±2.6)d,总住院时间为(52.2±6.4)d;实验组伤口平均愈合时间为(26.5±4.1)d,总住院时间为(35.8±2.7)d。经统计分析,两组患者的疗效、复发率和住院时间的差异具有统计学意义,P<0.05。结论:负压封闭引流联合抗生素植骨治疗慢性骨髓炎临床效果显著,值得进一步推广和应用。
Objective：To explore the clinical effect of chronic osteomyelitis with the treatment of vacuum sealing drainage（VSD）and antibiotic bone graft.Methods：Patients with chronic osteomyelitis in our hospital were retrospectively analyzed,for conventional treatment or VSD with antibiotic treatment.The outcomes were compared between VSD group and control group.Results：In control group,the total effective rate was 72.7%,the recurrence rate was 4.3%,the bacteria detection rate was 4.3%,the average healing time was（48.3±2.6）days,and the total hospital stay was（52.2±6.4）days.In VSD group,the total effective rate was 100%,the recurrence rate was 22.7%,the bacteria detection rate was 22.7%,the average healing time was（26.5±4.1）days,and the total length of hospital stay was（35.8±2.7）days.There were statistical differences in the curative effect,the recurrence rate and the length of hospital stay between the two groups（P〈0.05）.Conclusion：Vacuum sealing drainage with antibiotic bone graft for the treatment of chronic osteomyelitis showed remarkable clinical effect.
出处
《武汉大学学报（医学版）》
CAS
北大核心
2014年第5期804-807,共4页
Medical Journal of Wuhan University
关键词
负压封闭引流
抗生素
慢性骨髓炎
Vacuum Sealing Drainage Antibiotics Chronic Osteomyelitis
