摘要
建立了一种简单实用、经济高效的以邻碘苯胺、吡咯甲醛为起始原料,廉价的CuI为催化剂,价廉、易获得的2,2-联吡啶为配体,110℃条件下一锅法合成吡咯[1,2-a]喹喔啉类衍生物的催化体系,得到中等到优良产率.本方法具有催化剂廉价易得、操作简便、合成效率高的优点.
A simple, efficient, inexpensive one-pot method for the pyrrolo[1,2-a]quinoxaline derivatives synthesized from 2-formylazoles and o-aminoiodoarenes was developed by using cheap CuI as catalyst, inexpensive and readily available 2,2＇-bipyridine as ligand at 110 ℃. The reaction provides an efficient protocol to a series of pyrrolo[ 1,2-a]quinoxaline deriva- tives in good to high yields, and benefits of readily available catalyst and synthesis of high efficiency.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2014年第9期1845-1850,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21072095)
江苏省研究生创新工程(No.CXLX13_433)资助项目~~
