摘要
目的探讨妊娠期糖尿病应用糖化血清蛋白（GSP）及糖化血红蛋白（HbAlc）诊断的临床价值。方法入选我院2010年6月-2013年6月妊娠期糖尿病患者120例为观察组，同期择取120例正常妊娠孕妇为对照组，比较两组的GSP及HbAlc检测水平。结果观察组的GSP及HbAlc检测指标显著高于对照组（P〈0．05）；观察组的GSP及HbAlc异常率显著高于对照组（P〈0．05）；妊娠期糖尿病诊断中GSP的阳性预测值、灵敏度、特异性等均显著优于HbAlc（p〈0．05）。结论妊娠期糖尿病患者应用糖化血清蛋白及糖化血红蛋白检测诊断效果确切，且糖化血清蛋白的阳性预测值更高，对诊断妊娠期糖尿病具有重要意义。
Objective To explore the clinical value of glycosylated hemoglobin （HbAlc） and glycosylated serum protein（GSP） in the diagnosis of gestational diabetes mellitus. Methods 120 cases with gestational diabetes in our hospital from June 2010 to June 2013 were selected as observation group, and another 120 normal pregnant women selected as control group during the same period. GSP and HbAlc levels between two groups were compared. Results The GSP and HbAlc lev- els of the observation group were significantly higher than those of the control group （p 〈0.05 ）. Abnormal rates of GSP and HbAlc in the observation group were significantly higher than those in the control group （p 〈 0.05 ）. GSP for diagnosis of ges- tational diabetes was significantly better than HbAlc in the positive predictive value, reliability, sensitivity and specificity （p 〈 0.05 ）. Conclusion The glycosylated serum protein and hemoglobin have exact effect in the diagnosis of gestational di- abetes. The glycosylated serum protein is higher in positive predictive value, which is of great significance in the diagnosis of gestational diabetes mellitus.
出处
《现代医院》
2014年第9期69-70,共2页
Modern Hospitals
关键词
临床价值
妊娠期糖尿病
糖化血清蛋白
糖化血红蛋白
Clinical value, Gestational diabetes, Glycosylated hemoglobin, Glycosylated serum protein
