摘要
目的：探讨自拟复荣通脉胶囊治疗糖尿病周围神经病变的临床疗效。方法：将100例糖尿病周围神经病变患者,根据随机数字表法分为两组。其中对照组予甲钴胺1.0mg加生理盐水250mL静脉滴注,1次/d。治疗组在对照组基础上加服复荣通脉胶囊,5粒/次,3次/d,治疗21d。分析比较治疗前后临床症状,运动神经及感觉神经传导速度（SCV）改善情况。结果：治疗组总有效率86%,对照组总有效率72%。治疗组明显优于对照组（P〈0.01）。治疗组在改善患者肢体疼痛、麻木、发凉、感觉减退症状方面有效率达82.9%∽89.4%,优于对照组62.2%∽72.3%（P〈0.05）。治疗后治疗组、对照组的感觉神经传导速度及运动神经传导速度均有不同程度的改善;治疗组改善明显且优于对照组（P〈0.05,P〈0.01）。结论：复荣通脉胶囊组方能明显改善糖尿病周围神经病变患者的临床症状,并且能明显改善患者胫腓神经传导速度,同时与营养神经的药物合用能明显提高疗效,而且无其他不良反应,对糖尿病性周围神经病变有防治作用。
Objective： To investigate clinical efficacy of the Furong Tongmai capsule on diabetic peripheral neuropathy. Methods： 200 patients were divided into the treatment group and the control group according to the random number table. The control was treated with 1.0mg mecobalamin plus 250mL normal saline daily, the treatment was given the Furong Tongmai capsule more, five capsules each time, tid. In 21 days, clinical symptoms, status of motor nerve and sensory nerve conduction velocity were observed before and after treatment. Results： The total efficacy in the treatment and the control were 86% and 72% respectively, efficacy in the treatment was better than that in the control （P〈0.01）. The efficiency of symptom improvement in the treatment was 82.9%∽89.4%, including limb pain, numbness, cold and hypaesthesia, it was better than the control （62.2%∽72.3%）, the difference was statistically significant （P〈0.05）; motor nerve and sensory nerve conduction velocity in both were improved, the status in the treatment was better than the control （P〈0.05, P〈0.01）. Conclusion： The Furong Tongmai capsule was effective on diabetic peripheral neuropathy, could improve tibiofibular nerve conduction velocity. The Furong Tongmai capsule plus the neural nutrition medicine could significantly improve the efficacy, without side reactions.
出处
《中医临床研究》
2014年第25期63-64,66,共3页
Clinical Journal Of Chinese Medicine
关键词
复荣通脉胶囊
甲钴胺
糖尿病周围神经病变
The Furong Tongmai capsule
Mecobalamin
Diabetic peripheral neuropathy
