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基质辅助激光解吸附电离飞行时间质谱在临床病毒学中的应用 被引量：2

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摘要 基质辅助激光解吸附电离飞行时间质谱(MALDI-TOF MS)是一种新型的微生物鉴定技术,具有准确、快速、高通量等特点,目前在细菌和真菌的鉴定方面已比较成熟,但在病毒方面应用较少。本文从病毒的诊断、分型及耐药基因检测3个方面对MALDI-TOF MS在临床病毒学中的应用作一综述。
作者 程敬伟 王贺 徐英春
机构地区 北京协和医院检验科 中国医学科学院北京协和医学院研究生院
出处 《临床检验杂志》 CAS CSCD 北大核心 2014年第9期685-686,共2页 Chinese Journal of Clinical Laboratory Science
基金 卫生公益性行业科研专项(201402001)
关键词 基质辅助激光解吸附电离飞行时间质谱 病毒 诊断 分型
分类号 R373 [医药卫生—病原生物学] R446.5 [医药卫生—诊断学]
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参考文献16

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同被引文献54

  • 1沈德新,杜江,封志纯.新生儿常见感染病原菌的16SrDNA寡核苷酸阵列快速诊断[J].中华儿科杂志,2004,42(9):668-672. 被引量：4
  • 2张莉,杨持,其木格,王宝忠,武书丽.新生儿呼吸道微生态平衡动态研究[J].中国公共卫生,2007,23(11):1305-1306. 被引量：10
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  • 10Mather CA,Rivera SF,Butler-Wu SM.Comparison of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization- time of flight mass spectrometry systems for identification of myco- bacteria using simplified protein extraction protocols [J].Clin Mi- crobiol,2014,52(1):130-138.

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临床检验杂志
2014年 第9期

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