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心外膜脂肪组织体积与钙化积分评价冠状动脉狭窄程度的价值比较 被引量:3

Clinical significance of volume of epicardial adipose tissue and calcification score on evaluating the degree of coronary artery stenosis
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摘要 目的 对比心外膜脂肪组织体积及钙化积分评价冠状动脉狭窄程度的差异.方法 行冠状动脉64层多排螺旋CT检查的临床疑似冠心病患者210例为研究对象.冠状动脉造影证实冠状动脉狭窄<50%为非冠心病组145例,≥50%为冠心病组65例.均在西门子definition工作站测量心外膜脂肪组织体积及钙化积分.结果 非冠心病组平均心外膜脂肪组织体积(100.0±46.5) cm^3,钙化积分(36.2±18.5)分;冠心病组平均心外膜脂肪体积(117.3±57.6) cm^3;钙化积分(413.3±67.5)分.两组间平均心外膜脂肪组织体积和钙化积分比较差异均有统计学意义(t值分别为2.316、6.564,P<0.05、P<0.01).ROC曲线表明,钙化积分对诊断冠心病狭窄的敏感性、特异性均高于心外膜脂肪体积.结论 钙化积分对预测冠状动脉狭窄程度的敏感性和特异性均高于心外膜脂肪组织体积. Objective To investigate the comparison of volume of epicardium adipose tissue and calcification score on evaluating the degree of coronary artery stenosis(CHD).Methods Two hundred and ten cases with suspected coronary artery disease scanned by the 64 multi slice CT (MSCT) were selected as our subjects.One hundred and forty-five cases were diagnosed non coronary heart disease by with 〈 50% coronary artery stenosis by coronary angiography and served as non-CHD group.Other 55 cases were diagnosed as CHD with coronary artery stenosis ≥ 50% and served as CHD group.The volume of epicardium adipose tissue and calcification score of all cases were calculated with Siemens definition workstation.Results The volume of epicardium adpose tissue and calcification score in patients of CHD group were (117.3 ± 57.6) cm^3 and (413.3 ± 670.5) %,significant different from that of non-CHD group ((100.0 ± 46.5) cm^3,(36.2 ± 118.5).The differences were statistically significant (t =2.316,6.564; P 〈 0.05,P 〈 0.01).ROC curves showed that the sensitivity and specificity of calcification score were higher than the methods of volume of epicardium adipose tissue in terms of the diagnosis of stenosis and coronary artery disease.Conclusion Calcification score is proved to be a better method of predicting the coronary artery stenosis.
出处 《中国综合临床》 2014年第9期939-941,共3页 Clinical Medicine of China
关键词 心外膜脂肪组织体积 钙化积分 多排螺旋CT 血管造影术 Epicardial adipose tissue volume Calcification Multi slice spiral computerizedtomography Coronary angiography
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