摘要
目的:探讨经胸超声心动图(Transthoracic echocardiography,TTE)在评估室间隔缺损(Ventricular septal defect,VSD)封堵术前、后心脏负荷、功能变化的应用价值。方法:回顾性研究2007年1月至2012年8月广西医科大学一附院62例成功实施经皮穿刺VSD封堵术的患者资料。术前经超声筛查,术后3天、术后3个月、术后6个月及术后1年分别行TTE复查,常规测量左房收缩末期前后径(Left atrium end-systolic diameter,LAESD)、左室舒张末期前后径(Left ventricular end-diastolic diameter,LVEDD)、左室收缩末期前后径(Left ventricular end-systolic diameter,LVESD)、左室舒张末期容积(Left ventricular end-diastolic volume,LVEDV)、左室每博输出量(Left ventricular stroke volume,LVSV)、右室舒张末期前后径(Right ventricular end-diastolic diameter,RVEDD)、主肺动脉中段内径(Main pulmonary artery,MPA)、左室射血分数(Left ventricular ejection fraction,LVEF)、左室短轴缩短率(Left ventricular fraction shortening,LVFS)、三尖瓣反流压差(Pressure gradient of tricuspid regurgitation,PGTR)。结果:术后3个月、术后6个月、术后1年LAESD、LVEDD、LVESD、LVEDV、LVSV、MPA均较术前降低(P<0.05),且术后3天LVEDD、LVEDV、LVSV、MPA均较术前降低(P<0.05),术后3天LAESD、LVESD较术前差异无统计学意义(P>0.05);术后3天PGTR较术前降低(P<0.05),术后3个月、术后6个月、术后1年较术后3天无统计学差异(P>0.05);术前、术后RVEDD、LVEF、LVFS差异无统计学意义(P>0.05)。结论:TTE对VSD封堵术后心脏功能变化的评估有重要临床指导意义。
Objective： To evaluate the values by indexes of cardiac load and function before and after ventricular septal defect （VSD） occlusion using transthoracic echocardiography （TTE）. Methods： 62 cases with VSD, who were operated by percutanous catheter occlusion successfully from Jan. 2007 to Aug 2012, were enrolled TTE was performed before and after operation at 3 days, 3 months, 6 months and 1 year. Left atrium end-systolic diameter （LAESD）, left ventricular end-diastolic diameter （LVEDD）, left ventricular end-systolic diameter（LVESD）, left ventricular end-diastolic volume（LVEDV）, left ventricular stroke volume（LVSV）, right ventricular end-diastolic diameter （RVEDD）, main pulmonary artery （MPA）, left ventricular ejection fraction （LVEF）, left ventricular fraction shortening （LVFS） and Pressure gradient of tricuspid regurgitation （PGTR） were obtained. Results： LAESD, LVEDD, LVESD, LVEDV, LVSV and MAP reduced at 3 months, 6 months and 1 year after operation compared with pre-VSD closure （P 〈0.05）. LVEDD, LVEDV, LVSV and MAP were decreased at 3 days after operation than pre-VSD （P〈0.05）. There was no obvious change in LAESD and LVESD at 3 days after operation than pre-VSD （P〉0.05）. PGTR was reduced at 3 days postoperation compared with pre-VSD（P〈 0.05）, while there was no obvious decrease at 3 months, 6 months and 1 year postoperation compared with 3 days （P〉0.05）. RVEDD, LVEF and LVFS had no significant change before and after occlusion （P〉0.05）. Conclusion： TTE plays an important clinical guiding role in evaluating cardiac function before and after occlusion of VSD.
出处
《现代生物医学进展》
CAS
2014年第31期6086-6089,共4页
Progress in Modern Biomedicine
基金
广西自然科学基金重点项目(GXNSFDA239002
1140003A-26)
关键词
超声心动图
室间隔缺损
封堵术
心脏功能
Echocardiography
Ventricular septal defect
Occlusion
Cardiac function
