摘要
对2320名早期妊娠（孕周＜12周）妇女进行甲状腺功能筛查,统计分析亚临床甲状腺功能异常的患病率,并进一步分析其与妊娠糖尿病的相关性.结果显示,2 320名妊娠早期妊娠妇女中,临床及亚临床甲状腺功能减退（甲减）共234例,患病率为10.1％,其中临床甲减8例,占全部妊娠妇女的0.34％;亚临床甲减226例,占9.74％.甲状腺功能亢进14例,患病率为0.6％.亚临床甲减组中有33.3％发生妊娠糖尿病,明显高于正常对照组12.9％.提示妊娠早期亚临床甲减可明显升高妊娠糖尿病的发生率,因此,孕早期进行甲状腺功能筛查尤为重要.
A screening of thyroid function was performed in 2 320 pregnant women whose gestational age was less than 12 weeks.The incidence of subclinical thyroid disease and its relationship with gestational diabetes mellitus were analyzed.The results showed that there were 8 patients （0.34％） with clinical hypothyroidism,226 （9.74％） with subclinical hypothyroidism,and 14 patients （0.6％） with hyperthyroidism among 2 320 pregnant women.The prevalence of gestational diabetes mellitus in pregnant women with subclinical hypothyroidism was apparently higher than that in normal pregnant women （33.3％ vs 12.9％,P＜0.05）,suggesting that the increased incidence of gestational diabetes mellitus seems to be related to subclinical hypothyroidism during early pregnancy.Therefore,it is important to screen the function of thyroid during early pregnancy
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2014年第9期747-748,共2页
Chinese Journal of Endocrinology and Metabolism
关键词
甲状腺功能减退
亚临床
妊娠糖尿病
Hypothyroidism, subclinical
Gestational diabetes mellitus
