摘要
患者男,38岁。四肢反复起水疱、大疱伴痒38年,右踝部溃烂3年。小腿水疱处皮损组织病理示:表皮下水疱形成。直接免疫荧光:Ig G、Ig A、Ig M、C3均阴性。右外踝溃疡边缘皮损组织病理示:角化过度,表皮增生肥厚,肿瘤位于真皮内,与表皮相连,由鳞状细胞组成的细胞团块,细胞排列紊乱,可见角珠及角囊肿。诊断:真皮性大疱性表皮松解症并发皮肤鳞状细胞癌。
A 38-year-old male presented a 38-year history of recurrent blisters and bullous with itching,right ankle ulceration for 3 years. Histopathology of leg blister showed the formation of subepidermal blister and the result of DIF demonstrated Ig G（-）,Ig A（-）,Ig M（-）,C3（-）. Histopathology of right lateral malleolus ulcer showed hyperkeratosis,epidermal hyperplasia hypertrophy,the tumors located in the dermis connecting with epidermis,cell mass composed of squamous cells,cells arranged in disorder,and the squamous pearl and keratin cyst were seen. Diagnosis of dermal epidermolysis bullosa complicating squamous cell carcinoma was made.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2014年第10期1063-1064,共2页
The Chinese Journal of Dermatovenereology
关键词
表皮松解
大疱性
真皮性
鳞状细胞癌
Epidermolysis,bullosa,dermal
Squamous cell carcinoma
