摘要
目的:了解抑郁障碍患者的共病特征以及中西医药物联合治疗分布情况。方法:全国19家三甲综合医院诊断抑郁障碍的住院患者信息,运用频数统计及关联规则方法进行分析。结果:抑郁障碍共病前3位的为高血压病(24.67%),冠心病(16.10%),脑梗死(12.89%),随着年龄段增长,高血压比例由6.51%逐渐变化为12.55%,16.33%,12.47%;冠心病比例由2.79%逐渐变化为5.69%,10.17%,14.22%;脑梗死比例由3.72%逐渐变化为6.27%,7.70%,12.25%。抗抑郁剂使用频率占77.18%,氟哌噻吨美利曲辛使用频率为20.95%;中成药活血化瘀通络类使用频率为59.97%,银杏叶提取物使用频率占27.91%。活血化瘀通络药与抗抑郁剂联合使用频率最高,尤其是舒血宁注射液与氟西汀的联合使用。结论:抑郁障碍共病率最高的3种疾病为高血压、冠心病、脑梗死,且随年龄增长其比例逐渐增高。氟哌噻吨美利曲辛及银杏叶提取物单药使用率最高,舒血宁注射液与氟西汀的联合使用率最高。
Objective：To understand the comorbid characteristics and distribution of combined treatment of Chinese and Western medicine in depressive patients.Method：The descriptive statistic method and association rule were used to analyze the data from19 general hospitals with 3-A level in China.Result：Among the depressive disorder,the most frequent co-morbid physical diseases included hypertension（24.67%）,coronary heart disease（16.10%） and cerebral infarction（12.89%）,and the proportion of comorbid changes with the increasing age,from 6.51%to 12.55%,16.33%and 12.47%for hypertension;from 2.79%to 5.69%,10.17%and 14.22%for coronary heart disease;from 3.72%6.27%,7.70%and 12.25%for cerebral infarction.The use frequency of the antidepressants is 77.18%,and the use frequency of flupentixol melitracen is 20.95%.The use frequency of Huoxue Huayu Tongluo of traditional Chinese medicine is 59.97%,with that of 27.91%for Ginkgo biloba extract.The combined use frequency of Huoxue Huayu Tongluo of TCM and the antidepressants is the highest,especially for the combined use of Shuxuening injection and fluoxetine.Conclusion：The most frequent comorbid diseases of depression include three kinds of diseases,such as hypertension,coronary heart disease and cerebral infarction,and its proportion gradually increased with the growth of age.The single use frequency of flupentixol melitracen and G.biloba extract is the highest,while the combined use of Shuxuening injection and fluoxetine is the highest.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2014年第18期3454-3461,共8页
China Journal of Chinese Materia Medica
基金
国家"重大新药创制"科技重大专项资助项目(2009ZX09502-030)
中国中医科学院基本科研业务费自主选题项目(ZZ0808016)
关键词
抑郁障碍
真实世界
共病
中西治疗
depressive disorder
real-world
comorbid
combined treatment of Chinese and western medicine
