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1,25(OH)2D3对系膜细胞的作用及机制 被引量:1

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摘要 近年来研究发现1,25-二羟维生素D3[1,25(OH)2D3]具有独立于钙磷调节之外的许多新功能,包括调节多种细胞的增殖与凋亡.研究显示1,25(OH)2D3能抑制肾小球系膜细胞增殖,促进其凋亡.本文就1,25(OH)2D3对肾小球系膜细胞的作用及机制研究进展综述如下.一、肾小球系膜细胞的功能肾小球内有三种固有细胞,即脏层上皮细胞、血管内皮细胞及系膜细胞(mesangial cells,MC).
作者 马莉 杨晓萍
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2014年第10期790-793,共4页 Chinese Journal of Nephrology
基金 国家自然科学基金(81160090)
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