摘要
目的：研究云实皮抗炎活性部位的化学成分.方法：采用硅胶柱色谱及Sephadex LH-20等色谱技术分离纯化,根据理化性质及波普数据鉴定结构.结果：从云实皮的醇提物活性部位分离得到9个化合物,结构鉴定为：（±）原苏木素B（1）,东莨菪亭-7-O-β-D-吡喃葡萄糖苷（2）,4-羟基-3-甲氧基苯-1-O-β-D-吡喃葡萄糖苷（3）,（1＇R,3＇S,5＇R,8＇S,2Z,4E）-二氢红花菜豆酸-3＇-O-β-D-吡喃葡萄糖苷（4）,（1 ＇R,3＇S,5＇R,8＇S,2E,4E）-二氢红花菜豆酸-3＇-O-β-D吡喃葡萄糖苷（5）,甘草素（6）,异莨菪亭（7）,7-羟基-3-（4＇-羟基亚苄基）-色原-4-酮（8）,3-去氧苏木查尔酮（9）.结论：化合物2～5,7为首次从该属植物中分离得到,6,8为首次从云实中分离的到.
Objective：To study the chemical constituents of the anti-inflammatory fraction of Caesalpinia decapetala.Method：The compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatography and their structures were determined by chemical evidence and pectral analysis.Result：Nine compounds were obtained from C.decapetala and they were identified as （±） protosappanin B （1）,scopoletin-7-O-β-D-glucopyranoside （2）,4-hydroxy-3-methoxypheny-1-O-β-D-glucopyranoside （3）,（1 ＇R,3＇S,5＇R,8＇ S,2Z,4E）-dihydrophaseic acid-3＇-O-β-D-glucopyranoside （4）,（1＇R,3＇S,5＇R,8＇S,2E,4E）-dihydrophaseic acid-3＇-O-β-D-glucopyranoside （5）,liquiritigenin （6）,isoscopoletin （7）,7-hydroxy-3-（4＇-hydroxybenzylidene）-chroman-4-one （8）,3-deoxysappanchalcone （9）.Conclusion：Compounds 2-5,7 were isolatedfrom thegenus C.for the firs time,and compounds 6,8 were obtained from the C.decapetala for the first time.
出处
《中国实验方剂学杂志》
CAS
北大核心
2014年第20期110-113,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
贵州省科学技术基金项目(20112289)
贵州省科技厅中药现代化项目([2011]5081
[2013]4001)
关键词
豆科
云实
化学成分
结构鉴定
Fabaceae
Caesalpinia decapetala
chemical constituents
structure determination
