摘要
目的负压治疗和湿性疗法是2种能够促进伤口愈合的新方法。文中观察比较负压伤口治疗(negative pressure wound therapy,NPWT)联合湿性疗法(moist wound therapy,MWT)与单纯使用MWT用于交通挤压伤伤口的效果。方法对入选的32例患者随机数字表法分为NPWT+MWT组和MWT组,每组16例,NPWT+MWT组采用负压治疗21d后使用标准湿性疗法至愈合,MWT组采用标准湿性疗法至愈合。观察指标:分别于治疗前,治疗后7、14、21d采用相同方法测量伤口面积、深度、潜行和肉芽组织覆盖伤口床的百分率,计算面积、深度、体积和最大潜行的缩小率并记录100%肉芽覆盖伤口床时间及愈合时间。结果 2组治愈率均为100%,NPWT+MWT组在负压伤口治疗后21d的伤口面积、体积、深度和最大潜行缩小率均优于MWT组(P<0.05);100%肉芽覆盖伤口床时间NPWT+MWT组短于MWT组[(25.00±5.77)d vs(41.25±18.32)d,P=0.000];NPWT+MWT组愈合时间较MWT组缩短2周左右,但差异无统计学意义[(67.63±22.38)d vs(83.56±55.31)d,P=0.597]。结论负压伤口治疗治疗适用于软组织挤压伤,结合湿性疗法可有效促进肉芽组织生长,有利于伤口缩小和愈合。
Objective Negative pressure wound therapy （NPWT） and moist wound therapy （MWT） are two new methods for wound care .Whether the united is better than the single .The study was to observe and compare the effects of using negative pres-sure wound therapy （ NPWT） combined with moist wound therapy （ MWT） and simple MWT in the treatment of traffic crush injuries . Methods 32 cases were randomly divided into two groups：intervention group and control group , 16 cases for each group .In interven-tion group, wounds were first treated by NPWT for 21 days, followed by standardized MWT till healing .In control group, wounds were treated by standardized MWT till healing .Consensus methods were applied in the measurements before treatment , 7 days, 14 days and 21 days after treatment .The measurements were involved in wound size , depth, undermined edge and the ratio of granulation tissue covering wound bed .Calculation were made on the construction rates of wound size , depth, volume and undermined edge along with re-cords of the time 100%granulation tissue covering wound bed and healing .The database was set up and statistical analysis were done by SPSS 16.0 software. Results The healing rate was 100%for both groups.During 21 days of treatment, the construction rates of wound size, volume, depth and undermined edge of intervention group were better than those of control group （P〈0.05）.The time 100%granulation tissue covering wound bed of intervention group was shorter than that of control group （[25.00 ±5.77] d vs [41.25 ±18.32]d, P=0.000）.The healing time of intervention group was about two weeks shorter than of control group , but with no significance（[67.63 ±22.38]d vs [83.56 ±55.31]d, P=0.597）. Conclusion NPWT is applicable to traffic crush injuries in combination with MWT , which could promote the growth of granulation tissue and help construct and heal the wounds .NPWT combined with MWT has prior effects to simple MWT .
出处
《医学研究生学报》
CAS
北大核心
2014年第9期955-958,共4页
Journal of Medical Postgraduates
基金
南京军区南京总医院科研基金(M2008001)
