摘要
目的:观察含氟涂料与含氟牙膏对釉质表面再矿化和抗酸作用。方法:取牛恒切牙制备釉质片;统一酸蚀脱矿后随机分为4组(n=3);分别为生理盐水(A组对照)、Duraphat含氟涂料(B组)、Fluor Protector含氟涂料(C组)、含氟牙膏规律处理(D组);处理期间标本置于人工唾液孵育2周;再次酸蚀;各阶段均用显微硬度仪测定釉面显微硬度、扫描电镜观察釉面,图像分析电镜下釉面微孔隙面积差异;统计分析。结果:首次酸蚀后釉面明显脱矿。分组处理2周,A组釉面再矿化不明显;B组和C组釉面形成涂料保护层;D组釉面可见明显再矿化。再次酸蚀后:A组和D组显微硬度下降,B组和C组涂料保护层有明显抗酸作用。再次酸蚀后,A组和D组釉面微孔隙面积增加(P<0.05),但D组小于A组(P<0.05);B组、C组无显著变化(P>0.05)。结论:含氟涂料在釉面形成保护层,具有抗酸蚀和促进釉面再矿化作用;含氟牙膏能促进脱矿釉面再矿化,抗酸作用较弱。
Objective：To investigate the ability of fluoride toothpaste and fluoride varnish on enamel remineralization and acid resist-ance.Methods：Enamel specimens were prepared from bovine incisors,and were randomly divided into 4 groups（n=3）after acid-etching by 37%phosphoric acid.Specimens in group A（control）was processed daily with normal saline;those in group B and C were treated once with Duraphat varnish and Fluor Protector varnish respectively;in group D was daily processed with fluoride toothpaste. All specimens were incubated in artificial saliva for 2 weeks.Then all specimens received acid-etching again.Micro-hardness test, SEM observation and image analysis were performed before and after each step.Results：After 2 weeks of processing,no remineraliza-tion was found in group A.Varnish layers were observed on the surface of specimens in group B and C.In group D remineralization was detected on the enamel surface.After re-etching,micro-hardness decreased in group A and D.Fluoride varnish layers in group B and C showed strong resistance to acid-etching.After re-etching,area of micro-holes in group A and D increased（P〈0.05 ）,but that in group D was smaller than in the control（P〈0.05）.No micro-hole was observed in group B and group C.Conclusion：Protec-tive layer formed on the enamel surface by fluoride varnish is resistant to acid-etching and promotes enamel remineralization.Fluoride toothpaste application can promote enamel remineralization,but with less resistance to acid.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2014年第5期611-615,共5页
Journal of Practical Stomatology
基金
陕西省社发攻关项目(编号:2011K12-40)
西安市医疗卫生应用研究项目(编号:SF1208)
关键词
牙釉质
再矿化
含氟牙膏
含氟涂料
抗酸
Enamel
Remineralization
Fluoride toothpaste
Fluoride varnish
Acid resistance
