摘要
目的探讨血清降钙素原（PCT）在成人肺炎支原体肺炎（MPP）及其合并细菌感染肺炎中的临床价值。方法临床确诊2013年6月~2014年6月广州中医药大学附属茂名市中医院成人肺炎支原体肺炎患者85例,其中合并细菌感染者20例,正常成人体检者40例做对照,采用酶联荧光免疫分析技术测定其血清PCT。结果 65例单纯成人MPP患者血清PCT为（0.04±0.01）μg/L,对照组为（0.03±0.01）μg/L,两者差异无统计学意义（P〉0.05）,20例合并细菌感染的成人MPP患者血清PCT为（1.20±0.56）μg/L,较单纯成人MPP患者血清PCT明显升高,差异有高度统计学意义（P〈0.01）。结论检测血清PCT有助于鉴别成人MPP是否合并细菌感染,并可进行病情监测和疗效的判断。这对临床医生合理使用抗生素具有重要的指导意义,值得临床推广应用。
Objective To explore the clinic value of serum procalcitonin（PCT） level of adult mycoplasmal pneumonia（MPP） combined with bacterial pneumonia. Methods 85 adult cases with MPP in the Affiliated Maoming TCM Hospital of Guangzhou University of TCM from June 2013 to June 2014 including 20 cases combined with bacterial pneumonia and 40 adult health volunteers as control group were detected serum PCT used enzymelinked immunosorbent assay（ELISA）. Results Serum PCT levels of 65 cases with MPP only were（0.04±0.01） μg/L, as compared to（0.03±0.01） μg/L in control group. There was no significant difference（P〉0.05）. Serum PCT levels of 20 cases with MPP combined with bacterial pneumonia were（1.20±0.56） μg/L, and they were significantly higher than serum PCT levels of control group（P〈 0.01）. Conclusion Detecting serum PCT is helpful in identifying whether adult MPP patients combined with bacterial pneumonia, moreover it can monitor state of illness and judge curative effect. It has guiding significance for doctors to use antibiotic rationally. It is recommended that the results can be used more widely in clinic.
出处
《中国医药导报》
CAS
2014年第30期20-22,共3页
China Medical Herald
基金
广东省茂名市科技计划项目(编号20140334)
关键词
肺炎支原体肺炎
细菌
降钙素原
Mycoplasmal pneumonia
Bacterial
Procalcitonin
