摘要
目的探讨南京市大气颗粒物（PM10）污染对心脑血管疾病死亡的影响。方法收集2011年1月1日-2012年12月31日南京市死因资料、大气污染物数据及相关气象资料，应用时间分层的病例交叉设计研究对数据进行分析。结果在控制当日气温、相对湿度的影响后，PM10日均浓度每增加10μg/m^3，滞后2d的总心脑血管疾病死亡发生的OR值为1．013（95％CI：1．005—1．021）；模型中加入s02后，PM10日均浓度每增加10μg/m^3，滞后2d的总心脑血管疾病死亡的OR值为1．004（95％CI：1．001—1．007），关联均有统计学意义（P〈0．05）。结论本研究区域内PM10浓度升高可能导致心脑血管疾病死亡危险增加。
Objective To explore the association between the concentration of PM10 and the cardio-cerebrovascular diseases death in Nanjing , China. Methods The data of daily death of cardio-cerebrovascular diseases, the meteorology and the air pollution were collected from January 1, 2011 to December 31, 2012. A time-stratified case-crossover design was used to evaluate association between cardio-cerebrovascular disease death outcomes and PM10. Results After adjustment of the temperature and the relative humidity, the OR of the cardio-cerebrovascular diseases death associated with each 10 μg/m^3 increment of PM10 2 d before was 1.013 （95%CI： 1.005-1.021）. After adjustment of S02, in multi-pollutant models, the OR of the cardio-cerebrovascular diseases death associated with each 10 μg/m^3 increment of PM10 2 d before was 1.004 （95%CI： 1.001-1.007）. Conclusion The increased level of ambient PM10 is positively associated with the cardio-cerebrovascular diseases death in the investigated area.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2014年第7期569-571,共3页
Journal of Environment and Health
基金
江苏省卫生厅医学科研面上项目(H201331)
江苏省预防医学基金(Y2013009)
江苏省医学创新团队与领军人才项目(LJ201129)
江苏省疾病预防控制中心"科教兴业"后备人才基金(JKRC2011027)
关键词
空气污染
颗粒物
PM10
心脑血管疾病
病例交叉研究
Air pollution
Particulate matter
PM10
Cardio-cerebrovascular disease
Case-crossover study
