摘要
目的:分析干预前后高位结扎联合腔内激光消融及泡沫硬化术围手术期抗菌药物的使用情况,为抗菌药物的合理使用及规范化管理提供依据。方法:分别抽取我院2011年1月至2012年3月(干预前)、2012年4月至2013年6月(干预后)行高位结扎联合腔内激光消融及泡沫硬化术各60例,进行回顾性调查分析,结合相关文件精神评价围手术期抗菌药物使用的合理性。结果:干预后该手术围术期预防性使用抗菌药物的比率从干预前的93.3%降至20.0%;使用品种从头霉素类转为第二代头孢菌素;用药疗程从干预前的2.5 d下降至<24 h。两组患者术后均未出现院内感染,伤口均为甲级愈合。结论:术前未出现肢体皮肤溃疡的患者行高位结扎联合腔内激光消融及泡沫硬化术大多数情况下可以不预防使用抗菌药物;伴非感染性的基础疾病、恶性肿瘤等可以不作为围手术期预防性使用抗菌药物的用药指征。
OBJECTIVE：To investigate the perioperative use of prophylactic antibiotics in patients undergoing high ligation plus endovenous laser ablation and foam sclerotherapy before and after intervention so as to provide reference for rational use and standardized management of antibiotics. METHODS：A total of 120 patients undergoing high ligation plus endovenous laser abla-tion and foam sclerotherapy including 60 before intervention（from Jan. 2011 to Mar. 2012）and 60 after intervention（Apr. 2012 to Jun. 2013）were analyzed with regard to the rationality of prophylactic use of antibiotics in accordance with the relevant documents. RESULTS：The ratio of prophylactic use of antibiotics decreased from 93.3% before intervention to 20.0% after intervention;the drugs used were shifted from cephamycins before intervention to the second-generation cephalosporin after intervention;the course of treatment decreased from 2.5 days before intervention to〈24 h after intervention. Infection occurred in neither groups. The first class wound healing was noted in both groups. CONCLUSIONS：In most cases,there is no need to use antibiotics for patients with-out preoperative limb skin ulcer undergoing high ligation plus endovenous laser ablation and foam sclerotherapy. Complicated by non-infective underlying diseases and malignant tumor and so on can not be regarded as the indications of perioperative use of pro-phylactic antibiotics.
出处
《中国医院用药评价与分析》
2014年第9期828-830,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
高位结扎术
腔内激光消融
泡沫硬化术
围手术期
抗菌药物
High ligation
Endovenous laser ablation
Foam sclerotherapy
Perioperative period
Antibiotics
