摘要
目的探讨Survivin在肾细胞癌(renal cell carcinoma,RCC)患者手术前后外周血中的表达变化及其意义。方法采用双抗体夹心酶联免疫吸附法(ELISA)检测30例RCC行肾癌根治术患者和10例非肿瘤原因切肾患者术前、术后外周血中survivin含量表达变化情况。结果 RCC组术前术后相比,术后明显下降,有显著统计学意义。结论肾细胞癌根治术后,survivin在外周血中含量随之明显下降,说明Survivin与RCC的预后有一定的关系。
Objective To study the expression and significance of survivin in Pre/Post operative peripheral blood of renal cell carcinoma（RCC） .Methods The content of survivin in Pre/Post operative peripheral blood of 30 patients with RCC and 10 non‐tumorous patients were detected by enzyme linked immunosorbent assay （ELISA） .Results Comparing with the content of pre‐operatively one day ,the content of postoperatively was decreasing .Conclusion The expression of suvrivin in peripheral blood of RCC patients was significantly decreasing after operation .It suggests that survivin was tightly related with the tumor＇s progno‐sis .
出处
《滨州医学院学报》
2014年第5期334-335,共2页
Journal of Binzhou Medical University
