摘要
目的分析高龄孕妇的胎儿染色体核型检查结果,探讨高龄妊娠胎儿染色体异常的风险。方法对1448例高龄孕妇行羊膜腔穿刺,抽取羊水细胞进行培养,制备染色体并对染色体核型进行分析。结果 1448例高龄孕妇,检出异常核型53例,其中常染色体数目异常39例,性染色体异常5例,其他结构异常9例。结论高龄孕妇进行羊水细胞产前诊断是必要的。
Objective： Analysis of the fetal chromosomal karyotype test results of advanced pregnant women, to explore the risk of advanced pregnant women fetal chromosomal abnormalities. Methods： A total of 1448 pregnant women with advanced maternal age were selected, then amniotic cells were obtained by amniocentesis and cultured, chromosomal karyotype analysis was conducted after preparing chromosomes. Results： Among the 1448 ferent prenatal diagnostic samples, there were 53cases of abnormal karyotypes, karyotypes, including 39 pregnant women with autosomal chromosomal numerical abnormality, 5 pregnant women with sex chromosomal abnormality, and 9 pregnant women with other chromosomal structural abnormality.Conclusions： Advanced pregnant women for prenatal diagnosis of amniotic cells is necessary.
出处
《中国优生与遗传杂志》
2014年第10期67-68,共2页
Chinese Journal of Birth Health & Heredity
关键词
高龄孕妇
羊水细胞
产前诊断
染色体核型
Advanced pregnant women
Amniotic cell
Prenatal diagnosis
Chromosomal karyotype
