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羟氯喹性视网膜病变及其检测 被引量：5

Hydroxychloroquine retinopathy and its screening test
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摘要 羟氯喹在临床上广泛应用于自身免疫性结缔组织病,羟氯喹性视网膜病变发病率低,但视觉损害严重。近年来一些新的技术应用于临床,可以早期发现羟氯喹性视网膜病变。本文仅就羟氯喹性视网膜病变概况和检测方法进展做一简要综述。 Hydroxychloroquine is an effective and safe drug for the treatment of connective tissue disorders.Although it is associated with a low incidence of retinopathy,it can still lead to potentially irreversible visual loss.Recently,some new tests are used for timely detection to find hydroxychloroquine retinopathy as early as possible.Following is a review of hydroxychloroquine retinopathy and its screening test.
作者 胡健 黄厚斌 魏世辉
机构地区 解放军总医院眼科
出处 《解放军医学院学报》 CAS 2014年第11期1171-1174,共4页 Academic Journal of Chinese PLA Medical School
基金 "十二五"国家科技支撑计划课题(2012BA108B06)~~
关键词 羟氯喹 视网膜 视野 多焦视网膜电图 光学相干断层扫描 hydroxychloroquine retina visual field multifocal electroretinography optical coherence tomography
分类号 R378 [医药卫生—病原生物学]
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参考文献32

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  • 6Salu P,Uvijls A,Van Den Brande P,et al.Normalization of generalized retinal function and progression of maculopathy after cessation of therapy in a case of severe hydroxychloroquine retinopathy with 19 years follow-up[J].Doc Ophthalmol,2010,120 (3):251-264.
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同被引文献54

  • 1Bhavsar KV, Mukkamala LK, Freund KB. Multimodal imaging in a severe case of hydroxyehloroquine toxicity[J]. Ophthalmic Surg Lasers Imaging Retina, 2015, 46(3): 377-379. DOI: 10. 3928/23258160-20150323-14.
  • 2Phillips BN, Chun DW. Hydroxychloroquine retinopathy after short-term therapy[J]. Retin Cases Brief Rep, 2014, 8(1):67- 69. DOI: 10.1097/ICB.
  • 3Chiang E, Jampol LM, Fawzi AA. Retinal toxicity found in a patient with systemic lupus erythematosns prior to 5 years of treatment with hydmxychloroquine[J]. Rheumatology (Oxford), 2014, 53( 11 ) : 2001. DOI: 10.1093/rheumatology/keu317.
  • 4Bae E J, Kim KR, Tsang SH, et al. Retinal damage in chloro- quine maculopathy, revealed by high resolution imaging: a case report utilizing adaptive optics scanning laser ophthalmoscopy[J]. Korean J Ophthalmol, 2014, 28(1); 100-107. DOI: 10.3341/kjo. 2014.28.1.100.
  • 5Kazi MS, Saurabh K, Rishi P, et al. Delayed onset ehloroquine retinopathy presenting 10 years after long-term usage of chloro- quine[J]. Middle East Aft J Ophthalmol, 2013, 20( l ): 89-91. DOI: 10.4103/0974-9233.106404.
  • 6Gorovoy IR, Gorovoy MS. Fnndus autofluorescence in hydroxy- chloroquine toxicity[J]. JAMA Ophthalmol, 2013, 131(4) : 506. DOI: 10.1001/j amaophthalmol.2013.593.
  • 7Stelton CR, .Connors DB, Walia SS, et al. Hydrochloroquine retinopathy: characteristic presentation with review of screening [J]. Clin Rheumatol, 2013, 32 (6): 895-898. DOI: 10.1007/s 10067-013-2226-2.
  • 8Bumett HK, Somani R. Clinically evident chloroquine toxicity undetected by multifoeal electroretinogram[J]. Can J Ophthalmol, 2012, 47(5) : 31-33. DOI: 10.1016/j.jejo.2012.03.049.
  • 9Lee WJ, Ko MK, Lee BR. Hydroxyehloroquine retinopathy combined with retinal pigment epithelium detachment[J]. Cutan Ocul Toxicol, 2012, 31(2): 144-147. DOI: 10.3109/15569527. 2011.627076.
  • 10Salu P, Uvijls A, van den Brande P, et al. Normalization of generalized retinal function and progression of maculopathy after cessation of therapy in a case of severe hydroxychloroquine retin- opathy with 19 years follow-up[J]. Doc Ophthalmol, 2010, 120 (3): 251-264. DOh 10.1007/s10633-010-9220-7.

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解放军医学院学报
2014年 第11期

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