摘要
目的 观察剖宫产术中输注不同剂量的缩宫素对产妇血压的影响.方法 选择行孕足月剖宫产的产妇60例,按随机数字表法分为A组、B组、C组,每组20例.三组均行连续硬膜外麻醉,胎儿娩出后均在子宫肌肉注射缩宫素10 U,继之A组5U、B组10U、C组20 U缩宫素加入500 ml乳酸钠林格注射液以10 ml/min的速度静脉输注,根据手术医师的判断,对子宫收缩不良者舌下含服0.2 mg米索前列醇,出现严重低血压者给予5 mg麻黄碱静脉注射,于麻醉前（T0）、胎儿娩出后（T1）及输注缩宫素后5 min（T2）、10 min（T3）、30 min（T4）记录平均动脉压（MAP）、心率以及麻黄碱和米索前列醇用量.结果 A组和B组各时间点MAP和心率比较差异无统计学意义（P＞0.05）;C组T2和T3时MAP明显低于A组和B组,心率明显快于A组和B组,差异有统计学意义（P＜0.05）.但A组有7例、B组有2例、C组有1例患者因子宫收缩不良而舌下含服米索前列醇0.2 mg;A组有1例、B组有3例、C组有8例患者因血压下降超过基础值20％而静脉注射麻黄碱5 mg.结论 剖宫产术中于胎儿娩出后在子宫肌肉注射缩宫素10U,继之将10U缩宫素加入500 ml乳酸钠林格注射液中以10 ml/min的速度静脉输注对产妇血压及心率的影响较小,并能达到满意的子宫收缩效果.
Objective To observe the effects of blood pressure by intravenous infusion of different doses ofoxytocin in cesarean section.Methods Sixty full-term pregnant women undergoing cesarean section with continuous epidural anesthesia were divided into three groups by random digits table method with 20 cases each：group A,B and C.Three groups were injected 10 U oxytocin in uterine muscle after infant delivery.Group A,B and C received 5,10 and 20 U oxytocin （sodium lactate ringer,500 ml） continuous intravenous infusion at the speed of 10 ml/min.If happened uterine contractions bad,they were sublingual administering 0.2 mg misoprostol.If happened severe hypotension,they were intravenous injected 5 mg ephedrine.The change of mean arterial pressure （MAP） and heat rate before anesthesia （T0）,after fetal childbirth （T1）,5 m in （T2）,10 min （T3）,30 min （T4） after infusion of oxytocin and the dosage of ephedrine and misoprostol were recorded.Results There were no significant differences in MAP and heart rate at every time point between group A and B （P〉 0.05）.MAP decreased and heart rate increased in group C at T2,T3 compared with those in group A and B,and there were significant differences （P〈 0.05）.The number of cases of sublingual misoprostol were increased in group A （7 cases） compared with that in group B （2 cases） and group C（1 case）.The 8 patients injected ephedrine in group C were more than group A（1 case） and group B （3 cases）.Conclusion Cesarean section after the delivery of the fetus in the uterus muscle injection of oxytocin 10 U,after 10 U of oxytocin added 500 ml sodium lactate ringer injection at the speed of 10 ml/min intravenous infusion has little effect on the blood pressure and heart rate,and has good uterine contractions.
出处
《中国医师进修杂志》
2014年第30期53-55,共3页
Chinese Journal of Postgraduates of Medicine
关键词
剖宫产术
催产素
血压
Cesarean section
Oxytocin
Blood pressure
