摘要
目的：探讨抗炎一号方治疗面部激素依赖性皮炎的临床疗效。方法收集2011年8月至2012年3月上海中医药大学附属曙光医院皮肤科门诊患者63例，均符合激素依赖性皮炎的诊断标准，按就诊顺序将患者随机分为两组，2组均停用激素，每晚口服西替利嗪10 mg。治疗组32例采用抗炎一号方加入面膜基质湿敷面部；对照组31例配合外敷天晴复欣。治疗前和治疗后每2周进行疗效指数评价、止痒程度比较。结果治疗后两组皮损程度评分均得到改善，其中治疗组皮肤油腻程度与脓疱积分[（0.13±0.35）分、（0.27±0.55）分],与对照组[（0.33±0.48）分、（0.42±0.46）分]比较，差异有统计学意义（P＜0.05）。治疗后两组皮损程度（EASI）评分、皮肤病生活质量指数量表（DLQI）、皮肤瘙痒程度积分[治疗组分别为（2.41±2.64）分、（4.93±2.90）分、（1.07±0.83）分，对照组分别为（2.52±2.73）分、（5.07±3.59）分、（1.30±0.65）分]均较同组治疗前[（4.63±4.02）分、（7.87±3.44）、（2.37±0.81）分，对照组分别为（4.63±4.02）分、（7.10±3.90）、（2.37±0.81）分]明显改善（P＜0.01或0.05），且治疗后两组DLQI指数、皮肤瘙痒程度积分比较，差异有统计学意义（P＜0.05）。结论抗炎一号方可有效改善激素依赖性皮炎患者皮肤的油腻程度和脓疱类皮损。
Objective To study the clinical effect ofKangyan-Yihao on facial steroid-dependent dermatitis.Methods 63 patients of steroid-dependent dermatitis in ShuGuang Hospital Affiliated to Shanghai University of TCM were recruited and randomly divided into a treatment group with 32 patients and a control group with 31 patients. Patients in both groups were forbidden to use hormone treatment and taken cetirizine 10 mg orally every night. On this basis, the treatment group was treated withKangyan-Yihao prescription and the control group was treated withTianQing-Fuxin. The total curative effects, itching-reliving degree and life quality were compared between the two groups after the treatment after two weeks.Results After the treatment, the EASI score, DLQI score skin itching score in the treatment group（2.41±2.64, 4.93±2.90, 1.07±0.83, respectively） were better than those in the control group（2.52±2.73,5.07±3.59, 1.30±0.65,P〈0.01 orP〈0.05）.ConclusionsKangyan-Yihao has a significant effect in treating facial steroid-dependent dermatitis, specially for the oily and pustule lesions.
出处
《国际中医中药杂志》
2014年第11期988-990,共3页
International Journal of Traditional Chinese Medicine
关键词
抗炎一号方
激素依赖性皮炎
面部
Kangyan-Yihao prescription
Steroid-dependent dermatitis
Face
