摘要
目的探讨淋巴结病变的特征性灌注模式,选取合适的参照条件鉴别诊断淋巴结性质。方法以病理结果为参照,定性分析78枚浅表淋巴结病变超声造影增强模式,并应用时间-强度曲线进行定量分析,比较不同参照条件下,良恶性淋巴结对应参数与周围组织、比邻动脉间差异。结果转移性淋巴结以不均匀高增强为主(7/17,41.2%),淋巴瘤主要表现为均匀高增强(2/4,50.0%),反应性增生主要表现为均匀高增强(24/52,46.2%)及无增强(6/52,11.5%),淋巴结结核主要表现为环形增强(2/4,50.0%);良性淋巴结超声均值、峰值强度及曲线下面积与比邻动脉差异有统计学意义(P<0.05),良性淋巴结超声均值、上升时间、达峰时间、峰值强度及曲线下面积与周围组织间差异均无统计学意义(P>0.05);恶性淋巴结超声均值及峰值强度与比邻动脉、周围组织间差异均有统计学意义(P<0.05),恶性淋巴结达峰时间与周围组织间差异有统计学意义(P<0.05)。结论不同类型浅表淋巴结病变存在不同的超声造影特征,以周围组织作为对比条件,进行时间-强度曲线分析,对于鉴别诊断淋巴结性质同样具有重要价值。
Objective To determine the perfusion pattern of lymphadenopathy in contrast-enhanced ultrasonography（CEUS）under different reference conditions.Methods The CEUS perfusion patterns of 78 superficial lymph node lesions were compared with their pathology results.Time-intensity curves were used for comparison between benign and malignant lymph nodes.Results Inhomogeneous hyperenhancement was the main perfusion pattern（7/17,41.2%）in metastatic lymph nodes;compared with homogeneous hyperenhancement（2/4,50.0%）in lymphoma,homogeneous hyperenhancement and isoenhancement（6/52,11.5%）in reactive lymph nodes,and circle enhancement（2/4,50.0%）in tuberculosis.Benign lymph nodes showed different mean value,peak intensity and area under the curve compared with their surrounding arteries（P〈0.05）.But the differences in mean value,rise time,time to peak,peak intensity and the area under the curve between benign lymphadenopathy and their surrounding tissues were not statistically significant（P〉0.05）.Malignant lymph nodes showed different mean value and peak intensity compared with their surrounding arteries and tissues（P〈0.05）.The differences in time to peak between malignant lymph nodes and their surrounding tissues were also statistically significant（P〈0.05）.Conclusion Different CEUS perfusion patterns are associated with different types of lymph node lesions.Time-intensity curves with surrounding tissues as reference condition offer great values for the differential diagnosis of superficial lymphadenopathy.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2014年第6期1005-1009,共5页
Journal of Sichuan University(Medical Sciences)
基金
四川省科技厅科技支撑计划项目(No.2012SZ0145)
成都市科技局项目(No.12PPYB053SF-002)资助
关键词
淋巴结
超声造影
增强模式
时间-强度曲线
Lymph nodes
Contrast-enhanced ultrasonography
Enhancement pattern
Time-
intensity curve
