摘要
目的：探讨短时受精后不同脱颗粒时间对体外受精胚胎移植周期的影响。方法：将行常规IVF治疗患者的同周期卵子分为两组（除去完全受精失败以及受精率低下的治疗周期），即短时受精即刻脱颗粒细胞组（A组：精卵孵育4h后即刻脱颗粒细胞）和短时受精并次日晨脱颗粒细胞组（B组：精卵孵育4h并受精后17～18h脱颗粒细胞），比较两组的受精率（2PN率）、多精受精率（多PN率）、卵裂率、优胚率、胚胎利用率、临床妊娠率。结果：两组的受精率（2PN率）、多精受精率（多PN率）、卵裂率、优胚率、胚胎利用率、临床妊娠率之间差异无统计学意义。结论：精卵孵育4h后去除颗粒细胞对受精、胚胎发育没有显著影响。
Objectives： To explore the effects of different degranulation cells time on in vitro fertilization and embryo transfer cycles after short - term fertilization. Methods： The oocytes in the same IVF - ET cycle were divided into two groups （ cycles with fertilization failure or low fertilization rate were not included）. Group A （ short - term fertilization and immediate degranulation, gamete co - incubating for 4 hours, then removing all degranula- tion cells）, group B （ short - term fertilization and degranulation in the morning on the next day, gamete co - incu- bating for 4 hours, then removing all degranulation cells 17 -18 hours after insemination）. The fertilization rate （two pronucleus rate）, the polyspermy rate （multiple pronucleus rate）, the cleavage rate, the good quality embryo rate, the embryo utilization rate and the pregnancy rate of the two groups were compared. Results： There was no statistically difference in the fertilization rate （two pronucleus rate）, the polyspermy rate （multiple pronucleus rate）, the cleavage rate, the good quality embryo rate, the embryo utilization rate and the pregnancy rate among the two groups. Conclusion ： Degranulation ceils removal after gamete co - incubating for 4 hours has no effect on ferti- lization, embryo development and embryo implantation.
出处
《中国性科学》
2014年第11期81-83,共3页
Chinese Journal of Human Sexuality
关键词
脱颗粒细胞
体外受精
胚胎发育
Degranulation cell
In vitro fertilization
Embryo development
