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急性肾损伤的肾脏替代治疗 被引量:1

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摘要 无论是发达国家还是发展中国家,急性肾损伤(AKI)的发病率及病死率均呈逐年升高趋势,据研究统计,约有35%以上的住院重症患者合并AKI。尽管医疗水平以及肾脏替代技术均在不断进步,但重症监护病房(ICU)患者的病死率仍高达30%-60%[1]。近期国内研究发现,急性肾损伤网络(AKIN)分期标准,多器官功能衰竭、急性重症胰腺炎、机械通气、脓毒血症以及ICU住院时间等均与AKI的不良预后相关[2]。此外,AKI的远期预后值得关注,研究表明5%的AKI患者肾功能不能恢复,另有5%的AKI患者虽然肌酐水平恢复正常,但出现持续性高血压、蛋白尿等。重症AKI患者的长期透析依赖率为5.3%-48%[3,4]。
出处 《中国医学前沿杂志(电子版)》 2014年第9期1-4,6,共4页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金 国家自然科学基金(81270818/81400746)
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参考文献9

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二级参考文献50

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