摘要
目的分析并探讨儿童肺炎支原体肺炎的临床特征以及红霉素与阿奇霉素序贯疗法的临床效果。方法选取来我院接受治疗的肺炎支原体肺炎患儿108例,随机分为阿奇霉素组与红霉素组,每组54例。回顾性分析108例患儿临床资料,总结临床特征。治疗方法：两组患者均给予常规的对症治疗,在此基础上阿奇霉素组给予阿奇霉素序贯疗法治疗,红霉素组给予红霉素序贯疗法进行治疗。结果 108例患儿均有发热和咳嗽症状,发热多表现为38.3℃～39.0℃,热型多为不规则热（32.41%）和稽留热（40.74%）,咳嗽多为阵发性干咳（66.67%）。X线检查支气管肺炎4例（3.70%）,间质性肺炎4例（3.70%）,均匀一致的片状阴影似大叶性肺炎改变88例（81.48%）,合并肺不张12例（11.11%）。MP-Ig M抗体阳性39例（36.11%）。阿奇霉素组显效32例,有效17例,无效5例,治疗有效率为90.74%;红霉素组显效26例,有效15例,无效13例,治疗有效率为75.93%。阿奇霉素组治疗有效率明显高于红霉素组（P〈0.05）。结论儿童肺炎支原体肺炎临床上多表现为发热和咳嗽,X线检查是本病重要诊断依据。与红霉素序贯疗法相比,阿奇霉素序贯疗法的治疗效果更加显著,临床上值得推广。
Objective To analyze and discuss the clinical characteristics of children with mycoplasma pneumonia, and clinical effects of erythromycin and azithromycin sequential therapy. Methods Selected children in our hospital for treatment of mycoplasma pneumonia, 108 patients were randomly divided into azithromycin group and erythromycin group, each group of 54 cases. 108 cases of children with clinical data were analyzed retrospectively, and clinical features were summarized. Treatment： all patients were treated with conventional symptomatic treatment, on the basis of azithromycin sequential therapy group received treatment with azithromycin, and erythromycin sequential therapy group received treatment with erythromycin. Results 108 cases had fever and cough, fever much performance was 38.3℃ -39.0℃, thermal model for irregular fever（32.41%） and continued fever（40.74%）, cough more for paroxysmal cough（66.67%）. X-ray bronchial pneumonia of 4 cases（3.70%）, interstitial pneumonia in 4 cases（3.70%）, uniform shape shadow seemed to change, 88 cases of lobar pneumonia（81.48%）, merging telecasts 12 cases（11.11%）. MP-Ig M antibody positive 39 cases（36.11%）. Azithromycin group 32 cases had marked effect, effective in 17 cases, invalid in 5 cases,the treatment effective rate was 90.74%; Erythromycin group of 26 cases were markedly effective, effective in 15 cases,13 cases of invalid, treatment effective rate was 75.93%. Treatment of efficient azithromycin group was obviously higher than that of erythromycin group（P〈0.05）. Conclusion Clinical child mycoplasma pneumonia symptoms are fever and cough, X-ray examination is an important basis for the diagnosis of this disease. Sequential therapy compared with erythromycin, azithromycin sequential therapy treatment effect is more significant, worthy of promotion clinic.
出处
《中国现代医生》
2014年第34期122-124,共3页
China Modern Doctor
基金
江西省景德镇市科技计划项目(sf20143213)
