摘要
目的探讨慢性阻塞性肺疾病急性加重期给予氨溴索序贯治疗的临床效果。方法 80例慢性阻塞性肺疾病急性加重期患者随机分为观察组和对照组,各40例。对照组给予常规治疗,观察组在常规治疗基础上给予氨溴索序贯治疗。观察两组患者治疗前和治疗后肺功能、C反应蛋白水平改变情况。结果观察组患者治疗前后的C反应蛋白水平降低值、一秒用力呼气容积(FEV1)、一秒用力呼气容积占用肺活量百分比(FEV1/FVC)升高值分别与对照组比较,差异有统计学意义(P<0.05)。观察组的总有效率高于对照组,差异有统计学意义(P<0.05)。结论氨溴索序贯治疗慢性阻塞性肺疾病急性加重期临床效果显著,值得借鉴。
Objective To explore the clinical effect of ambroxol sequential therapy in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods A total of 80 patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into observation group and control group, with 40 cases in each group. The control group was given routine treatment, while the observation group received additional ambroxol sequential therapy. The changes of the pulmonary function, and C-reactive protein were observed before and after treatment in the two groups. Results The decreased C-reactive protein level, and elevated levels of forced expiratory volume in 1 second （FEV1） and forced expiratory volume in 1 second / forced vital capacity （FEV1/FVC） after treatment in the observation group were compared with those before and after treatment in the control group, and the difference was statistically significant （P〈0.05）. The total effective rate of the observation group was higher than that of the control group, and the difference had statistical significance （P〈0.05）. Conclusion Ambroxol sequential therapy has precise effect in the treatment of acute exacerbation of chronic obstructive pulmonary disease, and it is worthy of reference.
出处
《中国现代药物应用》
2015年第1期5-6,共2页
Chinese Journal of Modern Drug Application
关键词
氨溴索
序贯治疗
慢性阻塞性肺疾病
急性加重期
Ambroxol
Sequential therapy
Chronic obstructive pulmonary disease
Acute exacerbation
