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青少年分化型甲状腺癌的研究进展 被引量:3

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摘要 青少年分化型甲状腺癌的临床特点与成人相比有以下特征:就诊时肿瘤体积更大,甲状腺结节恶性可能性更高,乳头状癌比例更高,更易出现颈淋巴结转移或远处转移,复发率较高,但总体预后较好。两者分子生物学特点也有所不同,青少年患者RET/PTC融合基因较常见,BRAF、RAS突变较少,且雌激素、c MET及HGF/SF在肿瘤发生、发展中起重要作用。
出处 《温州医学院学报》 CAS 2014年第10期777-780,共4页 Journal of Wenzhou Medical College
基金 浙江省自然科学基金资助项目(LY13H160034)
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