摘要
目的:探讨雷贝拉唑联合莫沙必利、熊去氧胆酸对不同民族反流性食管炎(reflux esophagitis,RE)的临床疗效.方法:选择2013-01/2014-06青海大学附属医院就诊的汉族、回族、藏族各60例RE患者,均服用雷贝拉唑、莫沙必利和熊去氧胆酸,8wk后观察3组临床症状及胃镜检查结果.结果:治疗后3组患者临床症状均明显减轻,3组总有效率无统计学差异(95.00% vs 91.67% vs 93.33%,P>0.05),3组均未出现严重不良反应.结论:雷贝拉唑联合莫沙必利、熊去氧胆酸治疗汉族、回族及藏族的RE效果良好,适宜推广.
AIM： To investigate the clinical efficacy of rabeprazole sodium combined with mosapride and ursodeoxycholic acid in the treatment of reflux esophagitis（RE） in patients of different ethnicity.METHODS： From January 2013 to June 2014, Han, Hui and Tibetan patients（n = 60 for each ethnicity） with RE were treated with rabeprazole sodium, mosapride and ursodeoxycholic acid. After 8 wk of treatment, clinical symptoms were observed, and gastroscopy examination was performed.RESULTS： After 8 wk of treatment, clinical symptoms were significantly reduced in all the three groups of patients; the total response rate had no statistical difference among the three group（95.00% vs 91.67% vs 93.33%, P〈0.05）; and no serious adverse reactions were observed in any group. CONCLUSION： Rabeprazole sodium combined with mosapride and ursodeoxycholic acid has good therapeutic effects on RE in Han, Hui and Tibetan patients.
出处
《世界华人消化杂志》
CAS
北大核心
2014年第31期4807-4809,共3页
World Chinese Journal of Digestology
关键词
雷贝拉唑
莫沙必利
熊去氧胆酸
反流性食管炎
Rabeprazole sodium
Mosapride
Ursodeoxycholic acid
Reflux esophagitis
