摘要
目的探讨2型糖尿病并发肾功能损伤的相关危险因素。方法选择2009年5月—2013年5月我院收治的2型糖尿病患者160例,根据病情分为观察组80例和对照组80例,收集两组患者的人口学信息,测定FBG、FBI、TG及CRP等生化指标,通过t检验和多元逐步回归分析方法进行危险因素分析。结果 FBG、FBI、TG、TCHO和LDL-C均明显高于对照组,ISI、HDL-C均低于对照组(P<0.05);CRP、FBG、GFR和UA是2型糖尿病并发肾功能损伤的高危因素(P<0.05)。结论高血压、高血糖、高血脂、炎症反应及胰岛素抵抗是2型糖尿病并发肾功能损伤的危险因素。
OBJECTIVE To discuss the related risk factor of type 2 diabetes complicated with renal function injury. METHODS There were 160 with type 2 diabetes who were admitted to hospital from May 2009 to May 2013. They were randomlydivided into control group that patients were type 2 diabetes complicated with renal function injury（80 cases）, and observation group that patients were type 2 diabetes simple（80 cases）. Collect demographic information and determine biochemical indicators such as FBG, FBI TG and CRP, the. Then,analysis risk factors via t examination and multivariate stepwise regression analysis method. RESULT The data of FBG, FBI, TG, TCHO, LDL--C in observation group were higher than control group.The level of ISI, HDL--C in observation group were lower than control group（P〈0.05）; The CRP, FBG, GFR and UA were risk factors of type 2 diabetes complicated with renal function injury（P〈0.05）. CONCLUSION The hypertension, hyperglycemia, hyperlipidemia, inflammation and insulin resistance were risk factors for type 2 diabetes complicated with renal function damage.
出处
《中国初级卫生保健》
2014年第11期124-125,共2页
Chinese Primary Health Care
