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青年直肠癌患者的血清瘦素与CEA,CA19-9的相关性分析

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摘要 目的探讨青年男性肥胖伴直肠癌患者中血清瘦素、CEA、CA19-9的水平及其瘦素与CEA,CA19-9的相关性。方法选择自2009年6—12月于本院初次经过肠镜及病理诊断明确的男性直肠癌患者20例,年龄范围在20-35岁,BMI≥25 kg/m^2;对照组为此期间体检正常者20例,其性别、年龄与患者组相匹配,BMI在18.5-23 kg/m^2。全部入选者于测定前12 h禁食,次晨排空大小便,于安静状态下测量体重与身高,然后抽取静脉血,用于检测血清CEA,CA19-9及瘦素水平。结果同正常对照组比较,直肠癌组患者的血清瘦素、CEA及CA19-9水平明显升高(P〈0.05),有统计学差异。但直肠癌患者血清瘦素与CEA,CA19-9无相关性(P〉0.05)。结论青年男性肥胖直肠癌患者中血清瘦素及CEA、CA19-9的含量均明显增加,但血清肿瘤标志物与瘦素水平无相关性。
作者 王德鑫 苗康
出处 《齐齐哈尔医学院学报》 2014年第22期3279-3280,共2页 Journal of Qiqihar Medical University
关键词 肥胖 瘦素 CEA CA19-9
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