摘要
目的调查肺癌患者围术期抗菌药物使用情况及存在问题,从而加强抗菌药物应用的管理,减少围术期医院感染。方法回顾性研究分析2012年1月1日-12月31日接受肺癌手术患者的临床信息和用药资料,调查分析抗菌药物使用及其合理性,数据采用SPSS 17.0软件进行统计分析。结果 521例肺癌手术患者中预防性抗菌药使用率为99.23%;药物使用频率前4位分别为头孢唑肟、拉氧头孢、头孢噻肟、头孢米诺,分别为41.59%、36.56%、7.16%、6.19%;治疗性抗菌药的病原菌送检率为45.21%,低于原卫生部要求。结论肺癌患者围术期预防性应用抗菌药物欠合理,与《抗菌药物临床应用指导原则》有差距,有待改善,合理用药需要进一步加强。
OBJECTIVE To investigate the condition and problems of perioperative antimicrobial use for lung cancer patients in our hospital ,so as to strengthen the management of antimicrobial usage ,reduce perioperative nosoco‐mial infection .METHODS Retrospective method was used to analyze the rationality of antimicrobial drug use for lung cancer patients accepted for operation from Jan .1 ,2012 to Dec .31 .Data were statistically analyzed with the software SPSS 17 .0 .RESULTS Of the 521 cases ,the use rate of prophylactic antimicrobials was 99 .23% .The top four antimicrobials and their related use frequency were ceftizoxime （41 .59% ） ,latamoxef （36 .56% ） ,cefo‐taxime （7 .16% ） ,cefminox （6 .19% ） ,respectively .The delivery rate of pathogenic bacteria was 45 .21% ,which was lower than the requirement by the Ministry of Health .7 CONCLUSION The prophylactic use of antimicrobials in perioperative period for lung cancer patients was less reasonable ,and failed to meet the requirements of the guidelines on clinical application of antimicrobials ,thus it is necessary to strengthen the rational use of antimicro‐bials .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第23期5828-5830,共3页
Chinese Journal of Nosocomiology
基金
浙江省医药卫生科技计划基金资助项目(2011KYB024)
关键词
肺癌
围术期
抗菌药物
Lung cancer
Perioperative period
Antimicrobial
