摘要
目的：探讨循证护理干预对保护血液透析患者残余肾功能的影响。方法以海南省农垦总医院2011年1月-2013年1月收治的80例尿毒症血液透析患者为研究对象，随机分为观察组与对照组，每组各40例。所有患者均按照医嘱，进行规律血液透析治疗，并给予相应药物及护理措施，观察组患者在此基础上增加循证护理干预。观察并比较两组患者治疗前后残余肾功能、尿量、白细胞介素（IL）-1β、IL-6和生活质量[生存质量（QOL）、Zung焦虑自评（SAS）和Zung抑郁自评（SDS）量表]。结果观察组患者干预后残存肾功能、尿量、IL-1β和IL-6分别为（3.00±0.41）mL/min、（720.07±101.30）mL、（15.32±1.65）ng/L和（154.03±19.98）ng/L，对照组分别为（2.67±0.31）mL/min、（650.21±121.08）mL、（22.08±3.39）ng/L和（221.07±40.10）ng/L，观察组患者残余肾功能和尿量大于对照组，IL-1β和IL-6水平低于对照组，差异均有统计学意义（P〈0.05）。观察组患者QOL、SAS及SDS量表评分[（63.36±12.02）、（65.00±4.98）、（64.03±4.90）分]均优于对照组[（54.01±11.47）、（71.30±5.39）、（70.06±6.65）分]，差异有统计学意义（P〈0.05）。结论循证护理干预措施可以有效保护血液透析患者的残余肾功能，减轻肾血管内皮损伤程度，改善患者生活质量。
Objective To analyze the effect of evidence-based nursing intervention in the protection of residual renal function in the patients with hemodialysis. Methods From January 2011 to January 2013, in Haina Provincal Nongken General Hospital, 80 patients needed hemodialysis were divided into observation group and control group, with 40 cases in each group. The control group was given conventional treatments and nursing plan and the observation group was given additional evidence-based nursing intervention plan. The difference of residual renal function, urine output, IL-1β, IL-6 and life quality （QOL, SAS, SDS） scores between the two groups were compared. Results After the treatment, the residual renal function of the observation group [（3.00±0.41） mL/min] was higher than that of the control group [（2.67±0.31） mL/min], the urine output of the observation group [（720.07±101.30） mL] was higher than that in the control group [（650.21±121.08） mL], the level of IL-1βof the observation group [（15.32±1.65） ng/L] was lower than that in the control group [（22.08±3.39） ng/L], the level of IL-6 of the observation group [（154.03±19.98） ng/L] was lower than that in the control group [（221.07±40.10） ng/L], the differences were statistically significant （P〈 0.05）. The scores of QOL, SAS and SDS of the observation group [（63.36±12.02）, （65.00±4.98）, （64.03±4.09） scores] were better than those of the control group [（54.01±11.47）, （71.30±5.39）, （70.06±6.65） scores], the differences were statistically significant （P〈0.05）. Conclusion It can get satisfactory effects to use evidence-based nursing intervention in the protection of residual renal function in the patients with hemodialysis.
出处
《中国医药导报》
CAS
2014年第35期99-102,共4页
China Medical Herald
关键词
循证护理
血液透析
残余肾功能
Evidence-based nursing
Hemodialysis
Residual renal function
