摘要
目的:探讨醒脑静联合尤瑞克林治疗急性脑梗塞患者临床疗效及其安全性评价,为临床诊断治疗提供科学依据。方法:102例患者随机分为对照组和观察组,对照组注射用尤瑞克林针,观察组在对照组基础上结合醒脑静治疗。结果:观察组治疗后总有效率和神经功能缺损评分显著高于对照组,且差异具有统计学意义(P<0.05);观察组治疗后MDA水平显著低于治疗前及同期对照组,且差异具有统计学意义(P<0.05);观察组治疗后SOD水平显著高于治疗前及同期对照组,且差异具有统计学意义(P<0.05);观察组治疗后血浆黏度、全血黏度及红细胞聚集指数显著低于治疗前,且差异具有统计学意义(P<0.05);两组不良反应发生率比较无统计学差异(P>0.05)。结论:醒脑静联合尤瑞克林治疗急性脑梗塞疗效显著,且无明显不良反应,值得临床应用推广。
Objective： To investigate the clinical efficacy and safety of Uribe Brooklyn and Xingnaojing treatment of a- cute cerebral infarction and to provide a scientific basis for clinical diagnosis and treatment. Methods ：102 patients were randomly divided into control group and observation group,51 cases in each. Control group was injected with Uribe Brook- lyn needle and treatment group added Xingnaojing. Results：The total treatment efficiency and neurological deficit scores were significantly higher in treatment group and the difference was statistically significant （ P 〈 0.05 ）. In observation group after treatment, MDA levels were significantly lower than that before the treatment and in control group at the same period and the difference was statistically significant （ P 〈 0.05 ）. SOD levels after treatment group were significantly higher than that before and that in control group at the same period and the difference was statistically significant （ P 〈 0.05 ）. After treatment, the observation group＇ s plasma viscosity, whole blood viscosity and erythrocyte aggregation index was significantly lower than those before treatment and the difference was statistically significant （P 〈 0.05 ）. There was no significant difference between the two groups＇incidence of adverse reactions （P 〉0. 05 ）. Conclusion： The combination of Uribe Brooklyn and Xingnaojing has significant effect in treating acute cerebral infarction and no significant adverse re- actions. It is worthy of clinical application and promotion.
出处
《中华中医药学刊》
CAS
北大核心
2015年第1期239-241,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
醒脑静
尤瑞克林
急性脑梗塞
疗效
安全性
Xingnaojing
Uribe Brooklyn
acute cerebral infarction
efficacy
safety
