摘要
目的:评价卡培他滨联合放疗治疗老年食管癌的疗效。方法:回顾分析30例≥70岁的老年食管癌患者经卡培他滨联合放疗治疗的疗效、生活质量和不良反应。结果:全组患者总有效率96.7%,1、2、3年生存率分别为96.7%、74.2%、50.8%;全组患者生活质量增加率为53.3%,稳定率为46.7%,无生活质量恶化患者。治疗过程中未出现Ⅳ级放化疗毒副反应;Ⅲ级白细胞减少发生率为10%;Ⅲ级放射性食管炎发生率为13.3%;无Ⅲ级恶心、呕吐及放射性气管炎病例发生;I、II级手足综合症发生率分别为23.3%(7/30),3.3%(1/30),未出现III级手足综合症病例。结论:卡培他滨联合放疗治疗老年食管癌疗效较好,患者的生活质量得以明显改善,不良反应轻微,值得临床进一步推广。
Objective：To evaluate the curative effect of capecitabine combined with radiotherapy in the treatment of elderly esophageal cancer.Methods：A retrospective analysis of 30 patients greater than or equal to 70-year-old elderly patients with esophageal cancer after capecitabine combined with radiotherapy efficacy quality of life and adverse reactions.Results：The total efficiency of all patients was 96.7％,1,2 and 3-year survival rates were 96.7％,74.2％,50.8％,respectively.53.3％ increased in the quality of life,stable rate was 46.7％,no deterioration of the quality of life.There was no grade Ⅳ radiotherapy and chemotherapy toxicity.Conclusion：Capecitabine combined with radiotherapy has good curative effect on elderly esophageal carcinoma,the patient＇s quality of life was significantly improved,and adverse reactions was mild.
出处
《现代肿瘤医学》
CAS
2015年第2期223-225,共3页
Journal of Modern Oncology
关键词
食管癌
放射治疗
卡培他滨
esophageal cancer
radiotherapy
capecitabine
