摘要
目的 观察血塞通软胶囊治疗脑梗死患者的临床效果.方法 收集2010年1-9月在河北联合大学附属医院门诊就诊的脑梗死患者112例,采用随机、双盲的方法将112例脑梗死患者随机分为试验组84例和对照组28例,分别给予血塞通软胶囊和银杏叶胶囊进行治疗,疗程均为28 d,以符合方案数据集（PPS）和全数据分析集（FAS）分析和比较两组患者治疗0、14、28 d时NIHSS脑卒中量表总分实测值历时性变化以及治疗前后的差值变化.统计分析采用SPSS13.5软件.结果 经PPS分析和FAS分析,对照组和试验组在治疗的各个时间段NIHSS脑卒中量表总分实测值组间比较,差异均无统计学意义（PPS分析,t值分别为0.500、0.218、0.012;FAS分析,t值分别为0.506、0.231、0.049,P均＞0.05）.两组患者在治疗的0d和28 d时间点组内的NIHSS脑卒中量表总分实测值随治疗时间延长而明显降低,差异均有统计学意义（PPS的F值分别为13.89、31.18;FAS的F值分别为14.80、34.04,P均＜0.05）.PPS分析和FAS分析结论一致.结论 血塞通软胶囊治疗脑梗死患者疗效确切,建议临床推广使用.
Objective To investigate the clinical effect of Xuesaitong soft capsule in the treatment of cerebral apoplexy in cerebral infarction patients.Methods One hundred and twelve patients with cerebral infarction were selected as our subjects,who were in out-patient clinic of Affiliated Hospital of Hebei United Univemity from Jan.to Sep.in 2010.The patients were randomly divided into experimemal group（84 cases） and control group（28 cases） and they were received Xuesaitong soft capsule or Ginkgo leaf capsule for 28d.To meet the program data set（PPS） and a full analysis of data set（FAS）,and compared NIHSS Stroke Scale score of the measured values of the diachronic changes at 0,14,28 d and the difference before and after treatment in the treatment of two groups of patients.Statistical analysis was done by SPSS13.5 software.Results PPS and FAS analysis showed that there were no statistic significance at each time of treated section in terms of the practical change value of cerebral apoplexy measuring scale between the experimental group and control group （（PPS：F between group：0.500,0.21 8,0.012 ; FAS：F between group：0.506,0.231,0.049 ; P 〉 0.05）.The practical change value of cerebral apoplexy measuring scale decreased obviously at 0 d and 28 d after treatment.The analysis of variance of repeated measured data indicated that there were obviously statistic significance（PPS：F inner group：13.89、31.18 ; FAS：F inner group：14.80,34.04 ;P 〈 0.05）.The analysis results were concordance through FAS and PPS.Conclusion The clinical effect of Xuesaitong soft capsule for cerebral infarction patients with cerebral apoplexy is safe,and it was suggested to apply in clinic.
出处
《中国综合临床》
2014年第12期1239-1242,共4页
Clinical Medicine of China
基金
唐山市科技局项目（09130202A-3-31）
关键词
血塞通软胶囊
脑梗死
脑卒中
Xuesaitong soft capsule
Cerebral infarction
Cerebral apoplexy
