摘要
目的:研究腰硬联合加氯胺酮麻醉在儿童手术中的临床效果。方法:选取遂川县妇幼保健院(以下简称"我院")80例择期手术的儿童患者,采用随机抽签法分为氯胺酮麻醉组(对照组)和腰硬联合加氯胺酮组(观察组)各40例,观察2组患者麻醉效果。结果:2组患儿麻醉后的各生命指标均维持在正常状态。2组患儿麻醉后的平均动脉压、心率及脉搏血氧饱和度比较,差异无统计学意义(P>0.05);观察组患儿氯胺酮使用量明显低于对照组,差异有统计学意义(P<0.05);观察组患儿术后清醒时间明显短于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为17.50%(7/40),对照组为77.50%(31/40),差异有统计学意义(P<0.05)。结论:应用腰硬联合加氯胺酮麻醉在儿童手术中的麻醉效果、安全性较好。
OBJECTIVE：To evaluate the clinical efficacy of combined spinal-epidural anesthesia plus ketamine in pediatric surgery. METHODS： A total of 80 children undergoing selective surgery in Suichuan County Maternity and Child Care Hospital （ hereinafter referred to as “our hospital”） were analyzed retrospectively, with 40 assigned to ketamine anesthesia group （ control group） and 40 combined spinal-epidural anesthesia plus ketamine group （ observation group）. RESULTS：The life indicators in both groups maintained at a normal state. No statistically significant differences were noted in mean arterial pressure,heart rate and pulse oxygen saturation between 2 groups（P〉0.05）;however, there were significant differences between the two groups in total dose of ketamine（P〈0.05） and in the postoperative recovery time（ P〈0.05 ）; the incidence of adverse reactions was 17-50%（ 7/40 ） in the observation group as compared with 77-50%（31/40）in the control group（P〈0.05）. CONCLUSIONS： Combined spinal-epidural anesthesia plus ketamine showed better anesthetic efficacy and less advers reactions in pediatric surgery than ketamine alone.
出处
《中国医院用药评价与分析》
2014年第12期1086-1087,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
腰硬联合
氯胺酮
儿童手术
Combined spinal-epidural anesthesia
Ketamine
Pediatric surgery
