摘要
目的建立藏药二十五味肺病胶囊的质量控制方法。方法用薄层色谱法（TLC）对二十五味肺病胶囊中主要成分进行定性鉴别,并对方中铁棒锤所含毒性成分乌头碱进行限量检查;以反相高效液相色谱法（RP-HPLC）测定方中甘草酸含量。结果甘草酸在0.5288~5.288μg范围内线性关系良好,甘草酸回收率为96.8%（n=7）,RSD=1.3%。结论以上方法可有效控制藏药二十五味肺病胶囊的产品质量。
Objective To establish a quality standard for Tibeten medicine Ershiwuwei Feibing Capusules. Methods TLC was adopted for identification of major constituents in Ershiwuwei Feibing Capusules, and the limit test of aconitine was carried out. RP-HPLC was used to determine the contents of glycyrrhizic acid. Results A good linear relationship of gycyrrhizic acid was achieved in the range of 0.5288-5.288 μg and the average recovery of glycyrrhizic acid was 96.8 %（n=7）, wirh RSD of 1.3 %。Conclusion This method is simple, rapid, accurate, and available for quality control of the preparation.
出处
《食品与药品》
CAS
2014年第6期417-421,共5页
Food and Drug
基金
青海省科技厅藏药新药开发重点实验室项目(2013-Z-Y08)
