摘要
目的 了解柳州市出生缺陷发生的变化趋势及流行病学特征，为开展出生缺陷病因研究及制订出生缺陷综合干预措施提供参考依据。方法 对2009～2013年柳州市范围内119家助产医院的围产儿出生缺陷监测资料进行统计分析。结果 5年共监测围产儿239343例，发现出生缺陷儿4324例，出生缺陷总发生率为18．07‰，整体呈现上升趋势（χ^2势＝44．393，P＜0．001）。出生缺陷发生率前5位顺位依次是先天性心脏病、多指／趾、外耳其他畸形、总唇裂、马蹄内翻足。缺陷发生率城镇（22．36‰）高于农村（14．94‰，（χ^2=194．909，P＜0．001）；男性（20．34‰）高于女性（15．33‰）（χ^2=84．584，P＜0．001）。结论 柳州市出生缺陷发生率处于较高水平，应有针对性的进一步加大出生缺陷的一、二级预防措施，加强优生优育宣传，提高孕前产前检查，以减少出生缺陷的发生与出生，提高人口素质。
Objective To analyze the variation and epidemiologic features of birth defects in Liuzhou City , so as to provide basis for analyzing etiology of birth defects and making interventional measures .Methods SPSS 13.0 software was used for statistical analysis of monitoring data of birth defects in 119 obstetric hospitals in Liuzhou city from 2009 to 2013.Results Totally 4 324 infants with birth defects were found among 239 343 perinatal infants, and the incidence was 18.07‰with an increasing trend （ χtrend2 =44.393, P＆lt;0.001）.The top five in the sequence of birth defects was congenital heart disease , multiple fingers/toes, other outer ear deformities , total cleft lip and horseshoe varus foot.Incidence of birth defects in town （22.36‰） was higher than in countryside （14.94 ‰） （χ^2=194.909,P〈0.001）, and that of the male （20.34‰） was higher than the female （15.33‰） （χ^2=84.584,P＆lt;0.001）.Conclusion The incidence of birth defects maintains relatively high level in Liuzhou City .Therefore, some targeted measures to strengthen primary and secondary prevention , enhance propaganda on healthy birth and child development , and increase antenatal check should be taken to reduce the incidence of birth defects and improve the quality of birth population .
出处
《中国妇幼健康研究》
2014年第6期1062-1065,共4页
Chinese Journal of Woman and Child Health Research
关键词
围产儿
出生缺陷
监测
流行特征
perinatal infant
birth defects
monitoring
epidemiological feature
