摘要
目的：采用系统评价和 Meta 分析方法比较乳腺手术患者行胸椎旁神经阻滞（TPVB）和全身麻醉（GA）的效果。方法检索 Medline、Springer、Cochrane 图书馆、CNKI、万方数据库及维普数据库，收集比较 TPVB 与 GA 在乳腺手术麻醉效果的随机对照试验（RCT）。应用 Stata 11.0和RevMan 5.1软件进行 Meta 分析。结果获得符合标准的 RCT 研究5个，共计295例患者，其中TPVB 组148例，GA 组147例。Meta 分析结果显示，TPVB 组术后疼痛评分明显高于 GA 组（SMD 2.59，95％CI 1.10～4.08），TPVB 组术后镇痛药使用例次明显少于 GA 组（RR 0.23，95％CI 0.15～0.37），TPVB 组术后恶心呕吐发生率明显低于 GA 组（RR 0.27，95％CI 0.12～0.61）。结论与GA 比较，TPVB 在乳腺手术后具有较高的疼痛评分和较低的镇痛药用量和不良反应发生率。
Objective To explore the effect of thoracic paravertebral block （TPVB）versus general anaesthesia （GA）on breast surgery.Methods Public databases were searched including Med-line and Springer,in order to collect randomized controlled trial （RCT）of the effects of TPVB and GA on breast surgery.The data of the meta-analysis was analyzed by Stata 11.0 and RevMan 5.1. Results There were five RCTs consisting of 295 patients with breast surgery,group TPVB （n=148） and group GA （n=147）.The overall results of meta-analysis showed that pain scores of group TPVB were higher than those of group GA for breast surgery patients （SMD 2.59,95%CI 1.10-4.08）,but the postoperative analgesic consumption and postoperative nausea or vomiting of group TPVB were lower than those of group G （RR 0.23,95%CI 0.15-0.37 and RR 0.27,95%CI 0.12-0.61,respec-tively）.Conclusion Compared with GA,TPVB has higher pain scores,lower postoperative anal-gesic consumption and postoperative nausea or vomiting.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2014年第12期1214-1217,共4页
Journal of Clinical Anesthesiology
关键词
胸椎旁神经阻滞
全身麻醉
乳腺手术
META
分析
Thoracic paravertebral block
General anesthesia
Breast surgery
Meta-analysis
