摘要
目的:分析比较先天性心脏病患儿手术前后血BNP的变化及临床意义。方法:对本院从2013年1月-2014年8月收治的60例先天性心脏病患儿进行研究,30例简单先天性心脏病患儿作为对照组,30例危重症先天性心脏病患儿作为试验组,对比分析两组患儿在手术前后血BNP变化,分析BNP在危重症先心病患儿术后心功能评定中的意义。结果:试验组先天性心脏病患儿手术前血BNP水平为(19.0±9.9)ng/L,术后5 min为(23±14)ng/L,术后24 h为(32±11)ng/L,较对照组差异有统计学意义(P<0.05)。结论:在临床中通过研究先天性心脏病患儿手术前后血BNP变化,可以得出血清BNP水平与相应心功能水平之间的内在联系,找到一种准确、快速了解心功能水平的方法,有助于保障患者的健康,值得在实际中推广。
Objective：To analysis and compare the changes and clinical significance of children with congenital heart disease before and after operation serum BNP.Method：60 cases of children with congenital heart disease in our hospital from January 2013 to August 2014 were selected to study,and were divided into control group and observation group. 30 cases of simple congenital heart disease patients were selected as the control subjects.30 patients with severe congenital heart disease in children of experimental group were selected as research object.Changes of blood BNP before and after operation of the two groups of children were comparative analysised, significance of BNP in the critically ill children with congenital heart disease in evaluation of cardiac function after operation was analysised.Result：The serum level of BNP before and after the experimental group of children with congenital heart disease operation was（19.0±9.9）ng/L,5 min after operation was（23±14）ng/L,24 h after the operation was（32±11）ng/L,compared with the control group, the differences were statistically significant（P〈0.05）.Conclusion：It can draw the internal connection between the level of BNP in serum and the corresponding level of heart function through the study of changes of blood BNP before and after operation in children with congenital heart disease in clinic.Find an accurate, quick method to understand the level of heart function is help to safeguard the health of patients,it is worthy to be popularized in practice.
出处
《中国医学创新》
CAS
2014年第36期54-57,共4页
Medical Innovation of China
基金
江西省卫生厅2013年科技计划项目(2013-3145)
关键词
先心病手术
先天性心脏病
BNP
临床意义
Congenital heart disease operation
Congenital heart disease
Brain natriuretic peptide
Clinical significance
