摘要
目的探讨病程中血小板参数变化与短暂性脑缺血发作(TIA)治疗转归的相关性,为临床治疗及判断预后提供可靠的依据。方法随机设立基本治愈组、治疗有效组、治疗无效组及健康对照组,n=43,其中前3组于入院后治疗前及入院后治疗第7天分别抽取肘静脉血检查血小板数量(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)等血小板参数,通过方差分析进行比较。结果入院后第7天TIA各组与健康对照组比较PLT明显降低(P<0.05),从低至高依次是治疗无效组、治疗有效组、基本治愈组;MPV明显增高(P<0.05),从低至高依次是基本治愈组、治疗有效组、治疗无效组。结论血小板参数的变化有助于判断TIA的治疗效果,对疾病的转归有很好的预警作用。
Objective To investigate the correlation between the changes of platelet parameter and the therapeutic prognosis of transient ischemic attack （TIA） and provide the reliable basis to clinical treatment and judging prognosis. Methods To set up randomly the cure group, the effective group, the ineffective group and the healthy control group, n = 43, the former three groups were extracted respectively elbow venous blood before and after treatment and checked the platelet count （PLT） ,the mean platelet volume （MPV） and the platelet distribution width （PDW）. To study and compare their results using the analysis of variance. Results Compared with the healthy control group after treatment, the PLT in each TIA group decreased （P 〈 0.05 ）, which from low to high followed by the ineffective group, the effective group and the cure group. On the contrary, MPV increased significantly （P 〈 0.05 ）, which from low to high followed by the cure group,the effective group and the ineffective group. Conclusion The change of the platelet parameter is useful for judging the curative effect of TIA. It also has a good warning effect to predict the therapeutic prognosis of TIA.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2014年第12期1087-1088,共2页
Journal of Apoplexy and Nervous Diseases
基金
广东省中山市医学科研项目(No.2014A020019)
