摘要
目的研究瑞舒伐他汀对脑梗死患者血流动力学的影响。方法选取2011年2月—2014年2月我院神经内科收治的脑梗死患者60例,按照随机数字表法分为治疗组和对照组,每组30例。两组患者均采用神经内科常规治疗,治疗组加用瑞舒伐他汀,治疗3个月后,观察两组患者脑血流动力学改变情况。结果治疗前,两组患者血流动力学指标比较,差异无统计学意义(P>0.05);治疗组患者治疗后双侧大脑动脉平均血流速度以及搏动指数较治疗前改善,差异有统计学意义(P<0.05);对照组患者治疗后血流动力学指标与治疗前比较,差异无统计学意义(P>0.05);治疗组患者治疗后双侧大脑搏动指数较对照组低,差异有统计学意义(P<0.05)。结论瑞舒伐他汀可有效改善脑梗死患者血流动力学指标,有助于患者恢复健康。
Objective To study the impact of rosuvastatin on cerebral hemodynamics of patients with cerebral infarc-tion. Methods A total of 60 patients with cerebral infarction were selected in Department of Neurology from February 2011 to February 2014,and they were divided into treatment group and control group according to random number table method,30 ca-ses in each group. both groups given routine neurology treatment,while treatment group given extra rosuvastatin. After 3 monthss of treatment,cerebral hemodynamic changes of the two groups were observed. Results Before treatment,there was no statisti-cally significant differences of hemodynamic index between the two groups（P 〉 0. 05）;after treatment,mean blood flow veloci-ty and pulse index of bilateral cerebral artery of treatment group were improved compared with before treatment,the differences were statistically significantly different（P 〈 0. 05）;but no statistically significant differences was found in control group（P 〉0. 05）;after treatment,pulse index of bilateral cerebral artery of treatment group was lower than those of control group,the difference was statistically significantly different（P 〈 0. 05）. Conclusion Rosuvastatin can effectively improve hemodynamics of patients with cerebral infarction,is helpful to the recovery.
出处
《临床合理用药杂志》
2014年第36期3-4,共2页
Chinese Journal of Clinical Rational Drug Use
