2Wills V L,Hunt D R.Pain after laparroscopic cholecysteetomy[J].Br JSurg,2000,87(3):273.
3Zhao M,Joo D T.Enhancement of spinal N-methyl-D-aspartate receptor function by remifentanil action at 8-opioid receptors as a mechanism for acute opioid-induced hyperalgesia or tolerance[J].Anesthesiology,2008,109(2):308.
4Bonica J J.Fundamentalconsiderations of chronicpain therapy[J].Postgrad Med,1993,53:81.
5Harvey R,Champe P.Opioid analgesics and antagonists[M].Lippincott:Philadelphia,992:133.
6Ritschel W A,Parab P V,Denson D D,et al.Absolute bioavailability of hydromorphone after peroral and rectal administration in humans:saliva/plasma ratio and clinical effects[J].J Clin Pharmacol,1987,27:647.
7Columba Quigley,M D,MRCP and Phil Wiffen,MRPharm S.A Systematic Review of Hydromorphone in Acute and Chronic Pain[J].Journal of Pain and Symptom Management,2003,25:169.
8Eddy N B.Dihydromorphinone hydrochloride[J].JAMA,1933,100:1032.
9Pigni A,Brunelli C,Caraceni A.The role of hydromorphone in cancer pain treatment:a systematic review[J].Palliat Med,2011,25(5):471.
2Felden L,Walter C,Harder S,et al.Comparative clinical effects of hydro- morphone and morphine:a meta-analysis[J].BrJ Anaesth,2011,107(3):319-328.
3Chang AK,Bijur PE,Baccelieri A,et al.Efficacy and safety profile of a single dose of hydromorphone compared with morphine in older adults with acute,severe pain:a prospective,randomized,double-blind clinical trial[J].AmJ Geriatr Pharmacother,2009,7(1):1-10.
4Kumar P,Sunkaraneni S,Sirohi S,et al.Hydromorphone efficacy and treat- ment protocol impact on tolerance and mu-opioid receptor regulation[J]. Eur J Pharmacol,2008,597(1/2/3):39-45.
5Turgeon J,G,Qning R,Sathyan G,et al.The pharmacokinetics of a long- acting OROS hydromorphone formulation[J].Expert Opin Drug Deliv,2010,7(1):137-144.
6Jeleazcov C,Saari TI,Ihmsen H,et al.Population pharmacokinetic mo- deling of hydromorphone in cardiac surgery patients during postoperative pain therapy[J].Anesthesiology,2014,120(2):378-391.
7Abrishamkar S,Eshraghi N,Feizi A,et al.Analgesic effects of ketamine infusion on postoperative pain after fusion and instrumentation of the lumbar spine:a prospective randomized clinical trial[J].Med Arh,2012,66(2):107-110.
8Lee SH,Lee CJ,Kim TH,et al.Novel Use of Hydromorphone as a Pretreat- ment Agent:A Double-blind,Randomized,Controlled Study in Adult Korean Surgical Patients[J].Curr Ther Res Clin Exp,2011,72(1):36-48.
9Chang AK,Bijur PE,Napolitano A,et al.Two milligrams i.v.hydromor- phone is efficacious for treating pain but is associated with oxygen desatu- ration[J].J Opioid Manag,2009,5(2):75-80.
10Chang AK,Bijur PE,Davitt M,et al.Randomized clinical trial comparing a patient-driven titration protocol of intravenous hydromorphone with tra- ditional physician-driven management of emergency department patients with acute severe pain[J],Ann Emerg Med,2009,54(4):561-567.
