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糖化血红蛋白在糖尿病和空腹血糖受损人群中的诊断价值研究

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摘要 目的探讨糖化血红蛋白在糖尿病和空腹血糖受损人群中的诊断价值。方法选取2012年1月至2013年1月间在本院健康体检的2型糖尿病患者520例,依据空腹血糖水平将本次入选研究对象分为糖尿病组和非糖尿病组,在非糖尿病组中同时符合Hb A1c<6.5%者依据空腹血糖水平分为2个亚组,分别为正常对照组(NC亚组)和空腹血糖受损组(IFG亚组)。对比Hb A1c诊断糖尿病和IFG的敏感性、特异性、阳性似然比和阴性似然比。结果对Hb A1c≥6.5%糖尿病进行诊断时,IFG敏感性为95.45%,特异性为95.18%,+LR为19.8,-LR为0.040;在诊断IFG时,IFG敏感性为25.41%,特异性为94.36%,+LR为4.6,-LR为0.81。结论 Hb A1c在糖尿病的诊断中具有较高的特异性和敏感性,在诊断IFG时有较高的特异性,但敏感性较低。
作者 潘明锐
出处 《中国医药指南》 2014年第36期99-100,共2页 Guide of China Medicine
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