期刊文献+

北京市5岁以下腹泻输液儿童病毒病原学分布及相关因素分析 被引量:14

Analysis on pathogen distribution and related factors of the diarrheal children under 5 years through intravenous infusion in Beijing City
原文传递
导出
摘要 目的 了解北京市5岁以下腹泻输液儿童的病毒病原学分布,探索病毒性腹泻相关因素。方法 2012年7月~2013年7月,应用横断面研究方法,在北京市3家儿童专科医院采集476份便标本,分别进行4种急性胃肠炎病毒检测,并对病原学分布及检测结果阳性的相关因素进行分析。结果 北京市5岁以下腹泻输液儿童急性胃肠炎病毒总阳性率为54.0%,4种急性胃肠炎病毒阳性率依次为轮状病毒28.8%,杯状病毒18.3%,肠道腺病毒10.7%,星状病毒4.0%。在高发季节发病,有呕吐症状,粪便性状非脓血便,非粘液便,便常规检测无白细胞,年龄在6个月以上的腹泻输液儿童,粪便检测出急性胃肠炎病毒的可能性较大。结论 儿童病毒性腹泻发病率不低于细菌性腹泻,值得关注。临床医生在秋冬季节发现无明显炎症反应,有呕吐的腹泻儿童,应首先考虑病毒性腹泻,少用或不用抗菌素。 Objective To know the pathogen distribution and the related factors of diarrheal children under 5 years through intravenous infusion. Methods From July 2012 to July 2013, 476 stool specimens were collected from 3 children hospitals in Beijing. The pathogen distribution and related factors of the children patients with positive acute gastvoenteritis viruses were analyzed. Results The total positive rate of acute gastroenteritis viruses was 54.0%. The positive rates were in the following order: RV 28.8%, HuCV 18.3 %, AdeV 10. 7%, AstV 4. 0%. Positive tests were mostly found in those children: who fell in high-occurrence season and with vomiting, elder than 6 months, without mucus, pus or white blood cell in the feces. Conclusions The morbidity of virus diarrhea was not lower than that of the bacterial diarrhea Correct diagnosis should be made in the children with nomiting and diarrhea in Autumn and winter by stool examination, as so to reduce the misuse of antibiotics.
出处 《中华疾病控制杂志》 CAS CSCD 北大核心 2015年第1期39-41,共3页 Chinese Journal of Disease Control & Prevention
基金 北京市自然科学基金(7132045)
关键词 腹泻 病原学分布 危险因素 Diarrhea Pathogen distribution Risk factors
  • 相关文献

参考文献6

二级参考文献40

  • 1叶新华,金玉,方肇寅,孙亚萍,谢华萍,章青,XiJiang,DuncanSteele,RogerGlass.兰州地区2004-2005年度婴幼儿病毒性腹泻的病原学研究[J].中华流行病学杂志,2006,27(2):117-122. 被引量:105
  • 2谢立,孙昼,黄仁杰,王国详,考庆君,邓晶.婴幼儿冬季腹泻危险因素分析[J].中国预防医学杂志,2007,8(4):356-359. 被引量:25
  • 3中华人民共和国卫生部疾病预防控制司.霍乱防治手册.第5版.1999.44-64,74-76.
  • 4Schwartz DC,Cantor CR.Separation of yeast chromosome-sized DNAs by pulsed-field gel electrophoresis.Cell,1984,37:67.
  • 5Sambrook,Fritsch EF,Maniatis T.分子克隆实验指南.第2版.金东雁,黎孟枫,译.北京:科学出版社,1998 336-339.
  • 6Parashar UD, Hummelman EG, Bresee JS, et al. Global illness and deaths caused by rotavirus disease in children [J]. Emerg Infect Dis, 2003,9(5) :565-572.
  • 7Parashar UD, Gibson CJ, Bresee JS, et al. Rotavirus and severe childhood diarrhea [J]. Emerg Infect Dis, 2006, 12 ( 2 ) : 304- 306.
  • 8Ren L, Gonzalez R, Xiao Y, et al. Saffold cardiovirus in children with acute gastroenteritis, Beijing, China [J]. Emerg Infect Dis, 2009,15(9) :1509-1511.
  • 9Gabbay YB, Linhares AC, Oliveira DS, et al. First detection of a human astrovirus type 8 in a child with diarrhea in Belem, Brazil: comparison with other strains worldwide and identification of possible three lineages [J]. Mem Inst Oswaldo Cruz, 2007 , 102 ( 4 ) : 531-534.
  • 10Boxman IL, Tilburg JJ, Te LN, et al. Detection of noroviruses in shellfish in the Netherlands [J]. Int J Food Microbiol, 2006,108 (3) :391-396.

共引文献119

同被引文献149

  • 1钱渊,袁丽娟,熊朝晖,张又,刘军,关德华,王之梁.在我国腹泻患儿中发现G9型轮状病毒感染[J].病毒学报,1994,10(3):263-267. 被引量:36
  • 2张丽杰,方安.中国婴幼儿轮状病毒腹泻的流行病学和疾病负担研究进展[J].中国计划免疫,2007,13(2):186-191. 被引量:123
  • 3胡亚美,江载芳主编.诸福棠实用儿科学[M].第7版.北京:人民卫生出版社,2005:1172-1175.
  • 4Hall A J, Lopman BA, Payne DC, et al. Norovirus disease in the United States [J]. Emerg Infect Dis, 2013, 19 (8) : 1198-1205. DOI: 10.3201/eid1908,130465.
  • 5Settling RE. Methods for current statistical analysis of excess pneumonia-influenza deaths [ J ]. Public Health Rep, 1963,78 (6) : 494-506. DOI: 10,2307/4591848.
  • 6Liao, CM, Chang SY, Chen SC, et al. Influenza-associated morbidity in subtropical Taiwan [J]. Int J Infect Dis, 2009, 13 (5) : 589-599. DOI: 10,1016/j.ijid,2008.09.019.
  • 7Wang XL, Wu SS, Maclntyre CR, et al. Using an adjusted Serfling regression model to improve the early warning at the arrival of peak timing of influenza in Beijing [J]. PLoS One, 2015,10(3) :e0119923. DOI: 10,1371/journal.pone.0119923.
  • 8Qu M, Deng Y, Zhang X, et al. Etiology of acute diarrhea due to enteropathogenic bacteria in Beijing, China[J]. J Infect 2012, 65 (3) :214-222. DOI: 10,1016/j.jinf,2012.04.010.
  • 9WHO/UNICEF. Diarrhoea: Why children are still dying and what can be done [ EB/OL]. (2009-10-14) [2015-04431 ]. http:// who. int/maternal _ child _ adolescent/documents/ 9789241598415/en/.
  • 10Sumbana J, Taviani E, Manjate A, et al. Genetic determinants of pathogenicity of Eseheriehia eoli isolated from children with acute diarrhea in Maputo, Mozambique [ J]. J Infeet Dev Ctries, 2015, 9(6) :661-664.

引证文献14

二级引证文献96

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部