摘要
目的对文冠果（Xanthoceras sorbifolium Bunge）果壳的化学成分进行研究,以期更好地开发利用文冠果果壳。方法采用制备薄层色谱、反复硅胶柱色谱、Sephadex LH-20柱色谱、开放ODS柱色谱和制备高效液相色谱等方法进行分离纯化,根据理化性质和波谱数据分析对化合物进行结构鉴定。结果共分离得到8个化合物,分别鉴定为对苯二酚（hydroquinone,1）、对羟基苯乙腈（4-hydroxybenzylcyanide,2）、花椒毒素（xanthotoxin,3）、木犀草素（luteolin,4）、山柰酚（kaempferol,5）、柚皮素-7-O-β-D-葡萄糖苷（naringenin-7-O-β-D-glucopyranoside,6）、槲皮苷（quercitrin,7）、二氢红花菜豆酸-3＇-O-β-D-葡萄糖苷（dihydrophaseicacid-3＇-O-β-D-glucopyranoside,8）。结论化合物1～4、6、8为首次从文冠果属植物中分离得到。
Objective To study the chemical constituents of the husks of Xanthoceras sorbifolium Bunge. Methods The chemical constituents were isolated and purified by various chromatographic methods including silica gel, Sephadex LH-20 and ODS column chromatography, preparative TLC and preparative HPLC. Lat- er, their structures were elucidated on the basis of spectral analysis and their physico-chemical properties. Re- sults Eight compounds were obtained and identified as hydroquinone（ 1 ） ,4-hydroxybenzylcyanide（2 ）, xan- thotoxin （3）, luteolin （ 4 ）, kaempferol （ 5 ）, naringenin-7-O-β-D-glucopyranoside （ 6 ）, quercitrin （ 7 ）, dihy- drophaseicacid-3 ＇-O-β-D-glucopyranoside （ 8 ）, respectively. Conclusions Compounds 1- 4,6 and 8 are isola- ted from Xanthoceras genus for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2015年第1期18-21,共4页
Journal of Shenyang Pharmaceutical University
关键词
文冠果
果壳
化学成分
结构鉴定
Xanthoceras sorbifolium
husk
chemical constituent
structure identification
