摘要
目的：荟萃分析无创机械通气（NIV）在急性肺损伤及呼吸窘迫综合征患者中的应用效果。方法：系统检索Cochrane数据库、EMBASE、MEDLINE、Pubmed、Web of science、清华同方数据库、万方数据库、维普数据库,收集无创机械通气在急性损伤或呼吸窘迫综合征治疗效果方面的文献,参照Cochrane系统评价的方法对资料进行统计分析。结果：最终有5篇文献179例患者纳入研究。按随机效应模型合并分析后发现,NIV组气管插管率显著低于常规氧疗组（OR=0.17,95%CI：0.04～0.67,P=0.01）;但死亡率并未较常规氧疗组有所减少（OR=0.32,95%CI：0.09～1.071,P=0.06）。结论：与常规氧疗相比,无创机械通气可以显著减少急性肺损伤及急性呼吸窘迫综合征患者气管插管率,但不能减低患者死亡率。
Objective：To make a meta-analysis of the application effect of noninvasive mechanical ventilation（NIV） in patients with acute lung injury and acute respiratory distress syndrome.Method：The literatures about the treatment effect of NIV in acute lung injury and acute respiratory distress syndrome in the Cochrane database,EMBASE,MEDLINE,Pubmed,Web of science,Tsinghua Tongfang database,Database,VIP database were selected systematically.The data with Meta method according to Cochrane system evaluation were statistically analyzed.Result：Five articles and 179 patients were included.Test of the analysis combined by random effects model showed that the endotracheal intubation rate of the NIV group was significantly lower than conventional oxygen therapy group（OR=0.17,95%CI：0.04-0.67,P=0.01）,but the mortality rate did not decrease compared with the conventional oxygen therapy group（OR=0.32,95%CI：0.09-1.071,P=0.06）.Conclusion：Compared with the conventional oxygen therapy group,NIV can significantly reduce the intubation rate of acute lung injury and acute respiratory distress syndrome,but can＇t reduce mortality.
出处
《中外医学研究》
2015年第2期147-149,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
无创机械通气
氧疗
急性肺损伤
呼吸窘迫综合征
系统评价
Noninvasive mechanical ventilation
Oxygen therapy
Acute lung injury
Respiratory distress syndrome
System evaluation
