摘要
目的 探讨老年消化性溃疡的发病病因、临床表现及内镜特点.方法 收集我院2012年1月～2013年12月住院的消化性溃疡患者273例,将其分为老年组和中青年组,对两组患者的病因、临床表现、内镜特征进行比较.结果 幽门螺杆菌（HP）感染并非老年消化性溃疡的主要病因,老年患者非甾体抗炎药（NSAID）溃疡发病率明显增加,是老年患者的重要病因.老年消化性溃疡多以呕血、黑便为临床首发症状,并发幽门梗阻、癌变的机率高于中青年组.老年组胃溃疡发病率高于中青年组,且巨大溃疡发生率较中青年组多见.结论 老年消化性溃疡临床症状不典型,因同时合并多种基础疾病而增加了复发率及病死率.应了解老年消化性溃疡的发病特点、临床特征及内镜表现,并进行针对性的治疗.
ObjectiveTo investigate the etiology,clinical characteristics and endoscopic features in senile peptic ulcer. Methods A retrospective analysis was performed in 273 patients with peptic ulcer in our hospital from Jan, 2012 to Dec,2013. The etiology, clinic and endoscopic features were compared between elderly （ 112 patients, 〉 60 years ） and non-elderly （ 161 patients, 〈 60 years） patients. Results Helieobacter pylori（HP） infection was not the major risk factor in senile peptic ulcer, but the incidence rate of ulcer caused by non-steroidal anti-inflammatory drug （NSAID）increased significantly. Initial symp- toms of senile peptic ulcer were hematemesis and melena. The incidence rates of pyloric obstruction and canceration were higher in elderly group than those in non-elderly group. Compared with non-elderly group, the incidence rates of gastric ulcer and giant ulcer were higher in the elderly group. Conclusion The clinical manifestations of peptic ulcer in elderly are atypical. The recurrence rate and mortality rate in- crease because of various underlying complicated diseases. Treatment should target on the clinical and en- doscopic characteristics in senile peptic ulcer.
出处
《临床内科杂志》
CAS
2014年第12期822-824,共3页
Journal of Clinical Internal Medicine
关键词
老年消化性溃疡
病因分析
临床特点
内镜表现
Peptic ulcer in elderly
Etiology analysis
Clinical characteristics
Endoscopic features
